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For implantation to take place the uterus must become receptive. Uterine receptivity involves much cross-talk between the embryo and the uterus, initiating changes to the endometrium. This stage gives a synchrony that opens a window of implantation that enables successful implantation of a viable embryo. [4]
How long does implantation last? Although most pregnancies are 40 weeks , the process of implantation represents only a fraction of that time. Implantation typically lasts only a few days.
This process is called zona hatching and it takes place on the sixth day of embryo development, immediately before the implantation process. The hatching of the human embryo is supported by proteases secreted by the cells of the blastocyst, which digest proteins of the zona pellucida, giving rise to a hole.
Fertilization was not understood in antiquity. Hippocrates believed that the embryo was the product of male semen and a female factor. But Aristotle held that only male semen gave rise to an embryo, while the female only provided a place for the embryo to develop, [5] a concept he acquired from the preformationist Pythagoras.
[5] [13] Pregnancy is "the presence of an implanted human embryo or fetus in the uterus"; implantation occurs on average 8–9 days after fertilization. [15] An embryo is the term for the developing offspring during the first seven weeks following implantation (i.e. ten weeks' gestational age), after which the term fetus is used until birth. [5]
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The germinal stage refers to the time from fertilization through the development of the early embryo until implantation is completed in the uterus. The germinal stage takes around 10 days. [2] During this stage, the zygote begins to divide, in a process called cleavage. A blastocyst is then formed and implanted in the uterus.
Advances in fertility technology like egg freezing and in-vitro fertilization have made pregnancy in your 40s and 50s even more possible. Just ask these women.