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Tough bundles of collagen called collagen fibers are a major component of the extracellular matrix that supports most tissues and gives cells structure from the outside, but collagen is also found inside certain cells. Collagen has great tensile strength, and is the main component of fascia, cartilage, ligaments, tendons, bone and skin.
Type I collagen is the most abundant collagen of the human body, consisting of around 90% of the body's total collagen in vertebrates. Due to this, it is also the most abundant protein type found in all vertebrates. Type I forms large, eosinophilic fibers known as collagen fibers, which make up most of the rope-like dense connective tissue in ...
Dense connective tissue, also called dense fibrous tissue, is a type of connective tissue with fibers as its main matrix element. [1] The fibers are mainly composed of type I collagen. Crowded between the collagen fibers are rows of fibroblasts, fiber-forming cells, that generate the fibers.
In cord arrangement, bundles of collagen and matrix are distributed in regular alternate patterns. In sheath arrangement, collagen bundles and matrix are distributed in irregular patterns, sometimes in the form of a network. It is similar to areolar tissue, but in DRCT elastic fibers are completely absent. [2]
In 1954, Ramachandran & Kartha (13, 14) advanced a structure for the collagen triple helix on the basis of fiber diffraction data. It consists of a triple helix made of the repetitious amino acid sequence glycine-X-Y, where X and Y are frequently proline or hydroxyproline. [2] [3] Collagen folded into a triple helix is known as tropocollagen.
[20] [21] Although there is no dense collagen network in adipose tissue, groups of adipose cells are kept together by collagen fibers and collagen sheets in order to keep fat tissue under compression in place (for example, the sole of the foot). Both the ground substance and proteins (fibers) create the matrix for connective tissue.
These cavities are actually artificial gaps formed from the shrinking of the cells during the staining and setting of the tissue for examination. The inter-territorial space between the isogenous cell groups contains relatively more collagen fibers, allowing it to maintain its shape while the actual cells shrink, creating the lacunae. This ...
Collagenous fibers: collagenous fibers are made of collagen and consist of bundles of fibrils that are coils of collagen molecules. Elastic fibers: elastic fibers are made of elastin and are "stretchable." Reticular fibers: reticular fibers consist of one or more types of very thin collagen fibers. They join connective tissues to other tissues.
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