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The absorbed dose can be a poor indicator of the biological effect of radiation, as the biological effect can depend on many other factors, including the type of radiation, energy, and type of tissue. The relative biological effectiveness can help give a better measure of the biological effect of radiation.
The radiation weighting conversion factor from absorbed dose to equivalent dose is 1 for gamma, whereas alpha particles have a factor of 20, reflecting their greater ionising effect on tissue. The rad is the deprecated CGS unit for absorbed dose and the rem is the deprecated CGS unit of equivalent dose, used mainly in the USA.
Radiation with higher LET and higher relative biological effectiveness (RBE) have a lower OER in mammalian cell tissues. [2] The value of the maximum OER varies from about 1–4. The maximum OER ranges from about 2–4 for low-LET radiations such as X-rays, beta particles and gamma rays, whereas the OER is unity for high-LET radiations such as ...
deterministic effects (harmful tissue reactions) due in large part to killing or malfunction of cells following high doses from radiation burns. stochastic effects, i.e., cancer and heritable effects involving either cancer development in exposed individuals owing to mutation of somatic cells or heritable disease in their offspring owing to ...
Radiobiology is the study of the action of ionizing radiation on living things, including the health effects of radiation in humans. High doses of ionizing radiation can cause damage to living tissue such as radiation burning and harmful mutations such as causing cells to become cancerous, and can lead to health problems such as radiation ...
Ionizing radiation can cause biological effects which are passed on to offspring through the epigenome.The effects of radiation on cells has been found to be dependent on the dosage of the radiation, the location of the cell in regards to tissue, and whether the cell is a somatic or germ line cell.
Nevertheless, the effects of low doses are mostly unknown so many regulations exist to avoid unnecessary risks, such as skin or internal exposure. Due to the low penetration power and many variables involved it is hard to convert a radioactive concentration to a dose. 1 μCi of P-32 on a square centimetre of skin (through a dead layer of a ...
Among the somatic effects, secondary cancer is the most important. It develops because radiation causes DNA mutations directly and indirectly. Direct effects are those caused by ionizing particles and rays themselves, while the indirect effects are those that are caused by free radicals, generated especially in water radiolysis and