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Inner ear regeneration is the biological process by which the hair cells and supporting cells (i.e. Hensen's cells and Deiters cells) of the ear proliferate (cell proliferation) and regrow after hair cell injury. This process depends on communication between supporting cells and the brain.
Epley maneuver. The Epley maneuver or repositioning maneuver is a maneuver used by medical professionals to treat one common cause of vertigo, benign paroxysmal positional vertigo (BPPV) [1] [needs update] of the posterior or anterior canals of the ear. [2]
The inner ear (internal ear, auris interna) is the innermost part of the vertebrate ear. In vertebrates , the inner ear is mainly responsible for sound detection and balance. [ 1 ] In mammals , it consists of the bony labyrinth , a hollow cavity in the temporal bone of the skull with a system of passages comprising two main functional parts: [ 2 ]
Deflections of the stereocilia in the opposite direction toward the shortest stereocilia causes transduction channels to close. In this situation, the hair cells become hyperpolarized and the nerve afferents are not excited. [7] [8] [9] There are two different types of fluid that surround the hair cells of the inner ear.
The utricle and saccule are the two otolith organs in the vertebrate inner ear. The word utricle comes from Latin uter 'leather bag'. The utricle and saccule are part of the balancing system (membranous labyrinth) in the vestibule of the bony labyrinth (small oval chamber). [1]
The otolith organs are beds of sensory cells in the inner ear, specifically small patches of hair cells. Overlying the hair cells and their hair bundles is a gelatinous layer and above that layer is the otolithic membrane. [1] The utricle serves to measure horizontal accelerations and the saccule responds to vertical accelerations.
The crista ampullaris itself is a cone-shaped structure, covered in receptor cells called "hair cells". Covering the crista ampullaris is a gelatinous mass called the cupula . Upon angular acceleration (rotation), the endolymph within the semicircular duct deflects the cupula against the hair cells of the crista ampullaris.
Perilymph and endolymph have unique ionic compositions suited to their functions in regulating electrochemical impulses of hair cells necessary for hearing. The electric potential of endolymph is ~80-90 mV more positive than perilymph due to a higher concentration of potassium cations (K +) in endolymph and higher sodium (Na +) in perilymph. [4]