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  2. Genetic causes of type 2 diabetes - Wikipedia

    en.wikipedia.org/wiki/Genetic_causes_of_type_2...

    However, single nucleotide polymorphism (SNP) is one of many mechanisms that leads to increased risk for type 2 diabetes. To locate genes and loci that are responsible for the risk of type 2 diabetes, genome wide association studies (GWAS) was utilized to compare the genomes of diabetic patient group and the non-diabetic control group. [4]

  3. Maturity-onset diabetes of the young - Wikipedia

    en.wikipedia.org/wiki/Maturity-onset_diabetes_of...

    Maturity-onset diabetes of the young (MODY) refers to any of several hereditary forms of diabetes mellitus caused by mutations in an autosomal dominant gene disrupting insulin production. [1] Along with neonatal diabetes , MODY is a form of the conditions known as monogenic diabetes.

  4. Epigenetics of diabetes type 2 - Wikipedia

    en.wikipedia.org/wiki/Epigenetics_of_diabetes_Type_2

    The PPARGC1A gene regulates genes involved in energy metabolism. [1] [2] Since type 2 diabetes is characterized by chronic hyperglycaemia as a result of impaired pancreatic beta cell function [3] and insulin resistance in peripheral tissues, [4] it was thought that the gene might be downregulated in type 2 diabetes patients through DNA methylation.

  5. Diabetes: Everything You Need to Know, from Symptoms to Treatment

    www.aol.com/diabetes-everything-know-symptoms...

    Several things can increase a person’s risk for type 2 diabetes. These include: Genetics and family history. ... it can indicate a need for improved management strategies, like medication ...

  6. Type 2 diabetes - Wikipedia

    en.wikipedia.org/wiki/Type_2_diabetes

    Type 2 diabetes makes up about 90% of cases of diabetes, with the other 10% due primarily to type 1 diabetes and gestational diabetes. [1] In type 1 diabetes, there is a lower total level of insulin to control blood glucose, due to an autoimmune -induced loss of insulin-producing beta cells in the pancreas .

  7. MODY 2 - Wikipedia

    en.wikipedia.org/wiki/MODY_2

    MODY 2 or GCK-MODY is a form of maturity-onset diabetes of the young. [1] It is due to any of several mutations in the GCK gene on human chromosome 7 for glucokinase. [2] Glucokinase serves as the glucose sensor for the pancreatic beta cell. Normal glucokinase triggers insulin secretion as the glucose exceeds about 90 mg/dl (5 mM).

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