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Larger white patches are more likely to undergo malignant transformation than smaller lesions. [3] White patches which have been present for a long period of time have a higher risk. [3] Persons with a positive family history of cancer in the mouth. [3] Candida infection in the presence of dysplasia has a small increased risk. [3]
Leukoedema lesions disappear when the mucosa is stretched, which helps to differentiate it from other white lesions in the mouth. [2] The differential diagnosis is with leukoplakia , oral candidiasis , oral lichen planus , white sponge nevus , morsicatio buccarum , [ 3 ] hereditary benign intraepithelial dyskeratosis and dyskeratosis congenita.
White sponge nevus (WSN) is an extremely rare autosomal dominant [4] condition of the oral mucosa (the mucous membrane lining of the mouth). It is caused by one or more mutations in genes coding for keratin , which causes a defect in the normal process of keratinization of the mucosa.
The Welsh data, gathered between 2012 and 2021, showed mouth cancer was twice as common in men as in women, with cases peaking between the ages of 60 and 69.
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Head and neck cancer is a general term encompassing multiple cancers that can develop in the head and neck region. These include cancers of the mouth, tongue, gums and lips (oral cancer), voice box , throat (nasopharyngeal, oropharyngeal, [1] hypopharyngeal), salivary glands, nose and sinuses. [5]
Oral cancer, also known as oral cavity cancer, tongue cancer or mouth cancer, is a cancer of the lining of the lips, mouth, or upper throat. [6] In the mouth, it most commonly starts as a painless red or white patch , that thickens, gets ulcerated and continues to grow.