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  2. Database of Molecular Motions - Wikipedia

    en.wikipedia.org/wiki/Database_of_Molecular_Motions

    The Database of Macromolecular Motions is a bioinformatics database and software-as-a-service tool that attempts to categorize macromolecular motions, sometimes also known as conformational change. [ 4 ] [ 5 ] [ 6 ] It was originally developed by Mark B. Gerstein , Werner Krebs , and Nat Echols in the Molecular Biophysics & Biochemistry ...

  3. Conformational change - Wikipedia

    en.wikipedia.org/wiki/Conformational_change

    A change in protein conformation produces a change in the net orientation of the dye relative to the surface plane and therefore the intensity of the second harmonic beam. In a protein sample with a well-defined orientation, the tilt angle of the probe can be quantitatively determined, in real space and real time.

  4. Protein dynamics - Wikipedia

    en.wikipedia.org/wiki/Protein_dynamics

    The presence of multiple domains in proteins gives rise to a great deal of flexibility and mobility, leading to protein domain dynamics. [1] Domain motions can be inferred by comparing different structures of a protein (as in Database of Molecular Motions ), or they can be directly observed using spectra [ 12 ] [ 13 ] measured by neutron spin ...

  5. Molecular biophysics - Wikipedia

    en.wikipedia.org/wiki/Molecular_biophysics

    A ribosome is a biological machine that utilizes protein dynamics. Molecular biophysics is a rapidly evolving interdisciplinary area of research that combines concepts in physics, chemistry, engineering, mathematics and biology. [1]

  6. Cytochrome P450 reductase - Wikipedia

    en.wikipedia.org/wiki/Cytochrome_P450_reductase

    Cytochrome P450 reductase (also known as NADPH:ferrihemoprotein oxidoreductase, NADPH:hemoprotein oxidoreductase, NADPH:P450 oxidoreductase, P450 reductase, POR, CPR, CYPOR) is a membrane-bound enzyme required for electron transfer from NADPH to cytochrome P450 [5] and other heme proteins including heme oxygenase in the endoplasmic reticulum [6] of the eukaryotic cell.

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  9. Molecular motor - Wikipedia

    en.wikipedia.org/wiki/Molecular_motor

    In general terms, a motor is a device that consumes energy in one form and converts it into motion or mechanical work; for example, many protein-based molecular motors harness the chemical free energy released by the hydrolysis of ATP in order to perform mechanical work. [1]

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