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The lack of effectiveness of commercially available Lactobacillus probiotics may be because most do not actually contain vaginal lactobacilli strains. [68] LACTIN-V is a live biopharmaceutical medication containing the vaginally important Lactobacillus crispatus which is under development for the treatment of bacterial vaginosis and recurrent ...
The inhibitory substances produced by vaginal Lactobacillus is a primary factor in protecting the vaginal microbiota, with organic acids, bacteriocins, and hydrogen peroxide. These act synergistically against infection by pathogens. Not all Lactobacillus spp. and not all strains within one Lactobacillus species exhibit all 3 mechanisms. [13]
Lactobacillus vaccines are primarily used in the therapy and prophylaxis of dysbiotic conditions of the vaginal ecosystem (bacterial vaginitis, [1] [5] [6] vaginal trichomoniasis, [1] [7] and to a lesser extent, vaginal candidiasis [7]). Secondarily, they are used in the prophylaxis and complementary treatment of various urogenital diseases, if ...
“The most common cause of vaginal odor is an imbalance in the normal flora in the vagina,” which causes a fishy odor, irritation, and thin to no vaginal discharge, says Dr. Streicher.
VMB is dominated mainly by Lactobacillus species. This is the list of organisms that are found in the lower reproductive tract of sexually mature women who are not immunocompromised . A partial description of pathogens that can be found in the lower and upper reproductive tract of women can be found in the article sexually transmitted infection .
Normal vaginal flora (left) is predominantly rod-shaped Lactobacilli, whereas in bacterial vaginosis (right) there is an overgrowth of bacteria, which can be of various species. Given the known microbial associations, lactobacilli are currently available as probiotics to help control urogenital and vaginal infections, such as bacterial ...
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