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2. Abituzumab - Wikipedia

   en.wikipedia.org/wiki/Abituzumab

   Abituzumab is a humanized IgG2 monoclonal antibody (mAb) targeted at CD51 (an integrin) currently in development by Merck KGaA Darmstadt, Germany in an attempt to prevent bone lesion metastases in castration-resistant prostate cancer. [1] [2]

3. Cixutumumab - Wikipedia

   en.wikipedia.org/wiki/Cixutumumab

   It is a fully human IgG1 monoclonal antibody directed against the human insulin-like growth factor-1 receptor with potential antineoplastic activity. Cixutumumab selectively binds to membrane-bound IGF-1R, thereby preventing the binding of the ligand IGF-1 and subsequent activation of PI3K / AKT signaling pathway.

4. Indium (111In) capromab pendetide - Wikipedia

   en.wikipedia.org/wiki/Indium_(111In)_capromab...

   Capromab is a mouse monoclonal antibody which recognizes a protein found on both prostate cancer cells and normal prostate tissue. It is linked to pendetide , a derivative of DTPA . [ 2 ] Pendetide acts as a chelating agent for the radionuclide indium-111 .

5. Some Are Calling Monoclonal Antibodies "A Game Changer" - AOL

   www.aol.com/calling-monoclonal-antibodies-game...

   While COVID-19 lands more people in hospitals, doctors are turning to monoclonal antibodies to help keep people out. Governor Greg Abbott was one of the latest political leaders to test positive ...

6. Ipilimumab - Wikipedia

   en.wikipedia.org/wiki/Ipilimumab

   Ipilimumab, in combination with nivolumab, is indicated for the treatment of adults and adolescents twelve years and older with microsatellite instability-high or mismatch repair deficient metastatic colorectal cancer that has progressed following treatment with a fluoropyrimidine, oxaliplatin, and irinotecan.

7. Tocilizumab - Wikipedia

   en.wikipedia.org/wiki/Tocilizumab

   It is a recombinant humanized monoclonal antibody of the immunoglobulin IgG1 subclass against the interleukin-6 receptor (IL-6R). [18] Interleukin 6 (IL-6) is a cytokine that plays an important role in immune response and is implicated in the pathogenesis of many diseases, such as autoimmune diseases, multiple myeloma and prostate cancer.

8. Monoclonal antibody therapy - Wikipedia

   en.wikipedia.org/wiki/Monoclonal_antibody_therapy

   Anti-cancer monoclonal antibodies can be targeted against malignant cells by several mechanisms. Ramucirumab is a recombinant human monoclonal antibody and is used in the treatment of advanced malignancies. [18] In childhood lymphoma, phase I and II studies have found a positive effect of using antibody therapy. [19]

9. List of therapeutic monoclonal antibodies - Wikipedia

   en.wikipedia.org/wiki/List_of_therapeutic...

   This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage. See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page.