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  2. Antidepressant discontinuation syndrome - Wikipedia

    en.wikipedia.org/wiki/Antidepressant...

    Occasionally symptoms can last up to one year. [3] They typically resolve within a day of restoring the medication. [20] Paroxetine and venlafaxine seem to be particularly difficult to discontinue, and prolonged withdrawal syndrome (post-acute-withdrawal syndrome, or PAWS) lasting over 18 months has been reported with paroxetine. [21] [22] [23]

  3. Mysterious 'Brain Zaps' Are Being Reported By Lexapro ... - AOL

    www.aol.com/mysterious-brain-zaps-being-reported...

    Online, people claim they get brain zaps after stopping use of drugs like Lexapro (escitalopram), Cymbalta (duloxetine), and Paxil (paroxetine), but they can happen when you stop taking any type ...

  4. 1 in 6 people who stop antidepressants face withdrawal ... - AOL

    www.aol.com/1-6-people-stop-antidepressants...

    Stopping imipramine (Tofranil), paroxetine (Paxil or Seroxat), and venlafaxine (Effexor)/ desvenlafaxine (Pristiq) was associated with a higher risk of severe symptoms compared to other ...

  5. Don’t go ‘cold turkey’ when coming off antidepressants ...

    www.aol.com/don-t-cold-turkey-coming-000100767.html

    Patients who wish to come off the drugs permanently should first agree with their doctor whether it is right to stop taking the medication, and, if so, the speed and duration of withdrawal from it ...

  6. List of withdrawn drugs - Wikipedia

    en.wikipedia.org/wiki/List_of_withdrawn_drugs

    Lack of efficacy as shown by PROWESS-SHOCK study [19] [20] [21] Ebrotidine: 1998 Spain Hepatotoxicity. [3] Efalizumab (Raptiva) 2009 Germany Withdrawn because of increased risk of progressive multifocal leukoencephalopathy [14] Encainide: 1991 UK, US Ventricular arrhythmias. [2] [3] Ethyl carbamate: 1963 Canada, UK, US Carcinogen. [22 ...

  7. Tapering (medicine) - Wikipedia

    en.wikipedia.org/wiki/Tapering_(medicine)

    In medicine, tapering is the practice of gradually reducing the dosage of a medication to reduce or discontinue it. Generally, tapering is done is to avoid or minimize withdrawal symptoms that arise from neurobiological adaptation to the drug.

  8. Switching Antidepressants: Safety, Side Effects & Other ... - AOL

    www.aol.com/switching-antidepressants-safety...

    The truth is, antidepressants don’t always work — at least, not all antidepressants work for everyone. In fact, it’s not uncommon for people to try multiple antidepressants before finding ...

  9. Development and discovery of SSRI drugs - Wikipedia

    en.wikipedia.org/wiki/Development_and_discovery...

    The work which eventually led to the discovery of fluoxetine began at Eli Lilly and Company in 1970 as a collaboration between Bryan Molloy and Ray Fuller. [10] It was known at that time that the antihistamine diphenhydramine showed some antidepressant-like properties. 3-Phenoxy-3-phenylpropylamine, a compound structurally similar to ...