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A cell containing Pappenheimer bodies is a siderocyte. Reticulocytes often contain Pappenheimer bodies. They are mostly observed in diseases such as myelodysplastic syndrome (MDS), sideroblastic anemia, hemolytic anemia, lead poisoning and sickle cell disease. They can interfere with platelet counts when the analysis is performed by electro ...
The Pappenheimer Case centered around a family who were tried and executed for witchcraft in 1600 in Munich, Bavaria, Germany.The family were executed, along with accomplices they were forced to name under torture, after a show trial as scapegoats for a number of unsolved crimes committed years back in a display of extreme torture intended to deter the public from crime. [1]
On the peripheral blood smear can be found erythrocytes with basophilic stippling (cytoplasmic granules of RNA precipitates) and Pappenheimer bodies (cytoplasmic granules of iron). [13] The anemia is moderate to severe and dimorphic. Microscopic viewing of the red blood cells will reveal marked unequal cell size and abnormal cell shape.
Pappenheimer may refer to: the regiment of cuirassiers led by Gottfried Heinrich Graf zu Pappenheim; the Pappenheimer rapier; a member of the noble house of Pappenheim, see Pappenheim (state) an inhabitant or native of Pappenheim; Pappenheimer family
[citation needed] In contrast to Pappenheimer bodies, they are negative with Perls' acid ferrocyanide stain for iron (i.e. no iron in basophilic stippling). [1] Basophilic stippling is indicative of disturbed erythropoiesis. It can also be found in some normal individuals. [2]
Rouleaux formation on wet smear. Rouleaux (singular is rouleau) are stacks or aggregations of red blood cells (RBCs) that form because of the unique discoid shape of the cells in vertebrates.
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A comprehensive diagram of human hematopoiesis. Granulopoiesis consists of 5 stages, in which the myeloblast is the first recognizable cell. Next in the differentiation sequence is the monoblast and the promyelocyte, which can develop into one of three different precursor cells: the neutrophilic, basophilic or eosinophilic myelocyte.