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Pellagra is a disease caused by a lack of the vitamin niacin (vitamin B 3). [2] Symptoms include inflamed skin, diarrhea, dementia, and sores in the mouth. [1] Areas of the skin exposed to friction and radiation are typically affected first. [1] Over time affected skin may become darker, stiffen, peel, or bleed. [1] [3]
Example of a label showing the amount of niacin (Vitamin B3), and specifying to be niacinamide in the ingredient section.. The United Stated adopted in 1942 the terms niacin to nicotinic acid and niacinamide to nicotinamide to avoid references to nicotine, [12] [13] the terms were incorporated into the United States Adopted Name [14] that was created later in 1961.
A man with pellagra, which is caused by a chronic lack of vitamin B 3 in the diet. Severe deficiency of niacin in the diet causes the disease pellagra, characterized by diarrhea, sun-sensitive dermatitis involving hyperpigmentation and thickening of the skin (see image), inflammation of the mouth and tongue, delirium, dementia, and if left untreated, death. [7]
People who have had stomach surgery for weight loss, older adults, and people with gastrointestinal conditions like Crohn’s disease and celiac disease are also at risk for a B12 deficiency, she ...
Nicotinamide (INN, BAN UK [2]) or niacinamide (USAN US) is a form of vitamin B 3 found in food and used as a dietary supplement and medication. [3] [4] [5] As a supplement, it is used orally (swallowed by mouth) to prevent and treat pellagra (niacin deficiency). [4]
Niacin is a precursor to nicotinamide (both are forms of vitamin B3), a necessary component of NAD+. [4]: 541 The causative gene, SLC6A19, is located on chromosome 5. [5] It is named after the British family, Hartnup, who had this disease. [citation needed]
High levels of niacin, an essential B vitamin, may raise the risk of heart disease by triggering inflammation and damaging blood vessels, according to new research. The report, published Monday in ...
The B 12 vitamin is not abundantly available from plant products [4] (although it has been found in moderate abundance in fermented vegetable products, certain seaweeds, and in certain mushrooms, with the bioavailability of the vitamin in these cases remaining uncertain), [5] making B 12 deficiency a legitimate concern for those maintaining a ...
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