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[1] [2] It is applied to the affected area as a lotion or shampoo. [3] Symptoms frequently return if treatment is stopped. [4] Side effects may include hair discoloration, skin irritation, and risk of systemic absorption and toxicity, among others. [1] Use is not recommended in children less than 2–5 years old.
Climbazole is a topical antifungal agent commonly used in the treatment of human fungal skin infections such as dandruff, seborrhoeic dermatitis and eczema. [2] Climbazole has shown a high in vitro and in vivo efficacy against Malassezia spp. that appear to play an important role in the pathogenesis of dandruff. [2]
Other options include topical or systemic spironolactone or flutamide, although they have a high incidence of feminising side effects and are better tolerated in female androgenic hair loss. More advanced cases may be resistant or unresponsive to medical therapy, however, and require hair transplantation .
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Sodium lauroyl sarcosinate , also known as sarcosyl, is an anionic surfactant derived from sarcosine used as a foaming and cleansing agent in shampoo, shaving foam, toothpaste, and foam wash products. [1] This surfactant is amphiphilic due to the hydrophobic 12-carbon chain and the hydrophilic carboxylate.
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