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The stratum spinosum (or spinous layer/prickle cell layer) [1] is a layer of the epidermis found between the stratum granulosum and stratum basale. [2] This layer is composed of polyhedral keratinocytes. [3] [4] These are joined with desmosomes. [3]
The epidermis is the outermost of the three layers that comprise the skin, the inner layers being the dermis and hypodermis. [1] The epidermis layer provides a barrier to infection from environmental pathogens [2] and regulates the amount of water released from the body into the atmosphere through transepidermal water loss.
The human stratum corneum comprises several levels of flattened corneocytes that are divided into two layers: the stratum disjunctum and stratum compactum. The skin's protective acid mantle and lipid barrier sit on top of the stratum disjunctum. [5] The stratum disjunctum is the uppermost and loosest layer of skin.
Spinous cells are found in the superficial layers of the skin. They are found in the stratum spinosum (prickly layer, spinosum layer), which lies above the stratum basale (basal layer) and below the stratum granulosum (granular layer) of the epidermis. The spinous cells are arranged several layers thick to form a net-like covering. [1]
The human skin is the outer covering of the body and is the largest organ of the integumentary system. The skin has up to seven layers of ectodermal tissue guarding muscles, bones, ligaments and internal organs. Human skin is similar to most of the other mammals' skin, and it is very similar to pig skin.
Keratinocytes are the primary type of cell found in the epidermis, the outermost layer of the skin. In humans, they constitute 90% of epidermal skin cells. [ 1 ] Basal cells in the basal layer ( stratum basale ) of the skin are sometimes referred to as basal keratinocytes . [ 2 ]
Atopic dermatitis (or eczema) is the most common inflammatory skin disease. Skin may slough in a peeling fashion. Contact dermatitis arises from contact with a skin irritant. The ensuing irritation can cause sores and skin sloughing. and Seborrheic dermatitis which is associated with skin shedding through dandruff.
The epidermis is the outermost cell layer of the primary plant body. In some older works the cells of the leaf epidermis have been regarded as specialized parenchyma cells, [1] but the established modern preference has long been to classify the epidermis as dermal tissue, [2] whereas parenchyma is classified as ground tissue. [3]