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An uncoupler or uncoupling agent is a molecule that disrupts oxidative phosphorylation in prokaryotes and mitochondria or photophosphorylation in chloroplasts and cyanobacteria by dissociating the reactions of ATP synthesis from the electron transport chain.
Mitochondrial uncoupling protein 2 is a protein that in humans is encoded by the UCP2 gene. [ 5 ] Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP).
The Mapei Group has been publishing a two-monthly magazine in Italian and English since 1991. Adriana Spazzoli was the editor-in-chief of the magazine called Realtà Mapei for 28 years until 2019. 160,000 copies of the magazine are distributed all over Italy and 22,000 copies of Realtà Mapei International are published worldwide.
A DPC is a durable, impermeable material such as slate, felt paper, metal, plastic or special engineered bricks [7] bedded into the mortar between two courses of bricks or blocks. It can often be seen as a thin line in the mortar near ground level. To create a continuous barrier, pieces of DPC or DPM may be sealed together.
Research into arching or compressive membrane action has continued over the years at Queen's University Belfast, with the work of Niblock, [26] [27] who investigated the effects of CMA in uniformly loaded laterally restrained slabs; Skates, [28] who researched CMA in cellular concrete structures; Ruddle, [29] [30] who researched arching action ...
Membranes used for membrane distillation (MD) inhibit passage of liquid water while allowing permeability for free water molecules and thus, for water vapour. [1] These membranes are made of hydrophobic synthetic material (e.g. PTFE, PVDF or PP) and offer pores with a standard diameter between 0.1 and 0.5 μm (3.9 × 10 −6 and 1.97 × 10 −5 ...
Structure of the human uncoupling protein UCP1. An uncoupling protein (UCP) is a mitochondrial inner membrane protein that is a regulated proton channel or transporter.An uncoupling protein is thus capable of dissipating the proton gradient generated by NADH-powered pumping of protons from the mitochondrial matrix to the mitochondrial intermembrane space.
Coupling with oxidative phosphorylation is a key step for ATP production. However, in specific cases, uncoupling the two processes may be biologically useful. The uncoupling protein, thermogenin—present in the inner mitochondrial membrane of brown adipose tissue—provides for an alternative flow of protons back to the inner mitochondrial ...