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Clindamycin is a lincosamide antibiotic medication used for the treatment of a number of bacterial infections, including osteomyelitis (bone) or joint infections, pelvic inflammatory disease, strep throat, pneumonia, acute otitis media (middle ear infections), and endocarditis. [5]
Clindamycin/benzoyl peroxide, sold under the brand name Benzaclin among others, is a topical gel used for the treatment of acne. [7] It is a fixed-dose combination of clindamycin , as the phosphate, an antibiotic ; and benzoyl peroxide , an antiseptic .
Clindamycin: Cleocin: Serious staph-, pneumo-, and streptococcal infections in penicillin-allergic patients, also anaerobic infections; clindamycin topically for acne: Possible C. difficile-related pseudomembranous enterocolitis: Binds to 50S subunit of bacterial ribosomal RNA thereby inhibiting protein synthesis. Lincomycin: Lincocin ...
Pseudomembranous enterocolitis resulting from clindamycin-induced disruption of gastrointestinal flora can be a lethal adverse event observed in several species when used in the veterinary clinic, particularly in horses. At extremely high doses of clindamycin, skeletal muscle paralysis has been demonstrated in several species.
It contains clindamycin, as the phosphate, a lincosamide antibacterial; adapalene, a synthetic retinoid; and benzoyl peroxide, an oxidizing agent. [2] It is applied to the skin . [ 2 ]
[12] [14] If the woman has a severe allergy to beta-lactams and the GBS isolated is susceptible to clindamycin then clindamycin is the recommended alternative. [14] For women with a high-risk penicillin allergy and whose GBS isolate is not susceptible to clindamycin intravenous vancomycin (20 mg/kg intravenously every 8 hours, with a maximum of ...
β-Lactam antibiotics are indicated for the prevention and treatment of bacterial infections caused by susceptible organisms. At first, β-lactam antibiotics were mainly active only against gram-positive bacteria, yet the recent development of broad-spectrum β-lactam antibiotics active against various gram-negative organisms has increased their usefulness.
1911 – Arsphenamine, also Salvarsan [1] 1912 – Neosalvarsan 1935 – Prontosil (an oral precursor to sulfanilamide), the first sulfonamide 1936 – Sulfanilamide 1938 – Sulfapyridine (M&B 693)