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FDA: Evaluating Cardiovascular Risk in New Antidiabetic Therapies to Treat Type 2 Diabetes [40] provides recommendations for the development of drugs and therapeutic biologics regulated within the Center for Drug Evaluation and Research at the Food and Drug Administration (FDA) for the treatment of diabetes mellitus. Specifically, this guidance ...
Find-a-Drug aimed to run a series of projects in parallel addressing a number of diseases which have a major impact on health. The project sought to collaborate with the world's leading experts including academics in each therapeutic area. [1]
The Washington Manual of Medical Therapeutics is a medical textbook first published in 1942 by Wayland MacFarlane, a professor at the Washington University School of Medicine and chief of the internal medicine ward. Described as the "bible of the medical ward" the Washington Manual of Medical Therapeutics is now in its Thirty-Sixth Edition and ...
The effective therapeutic index can be affected by targeting, in which the therapeutic agent is concentrated in its desirable area of effect. For example, in radiation therapy for cancerous tumors, shaping the radiation beam precisely to the profile of a tumor in the "beam's eye view" can increase the delivered dose without increasing toxic ...
Prucalopride is contraindicated where there is hypersensitivity to the active substance or to any of the excipients, renal impairment requiring dialysis, intestinal perforation or obstruction due to structural or functional disorder of the gut wall, obstructive ileus, severe inflammatory conditions of the intestinal tract, such as Crohn's disease, and ulcerative colitis and toxic megacolon ...
In addition, the Orange Book contains therapeutic equivalence evaluations (2 character rating codes) for approved multisource prescription drug products (generic drugs). These evaluations have been prepared to serve as public information and advice to state health agencies, prescribers, and pharmacists to promote public education in the area of ...
Manual therapy, or manipulative therapy, is a treatment primarily used by physical therapists and occupational therapists to treat musculoskeletal pain and disability. It mostly includes kneading and manipulation of muscles, joint mobilization and joint manipulation .
Bowel management is the process which a person with a bowel disability uses to manage fecal incontinence or constipation. [1] People who have a medical condition which impairs control of their defecation use bowel management techniques to choose a predictable time and place to evacuate. [1]