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Tolvaptan, sold under the brand name Samsca among others, is an aquaretic drug that functions as a selective, competitive vasopressin receptor 2 (V 2) antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH).
Tolvaptan phosphate is a drug used for the treatment of cardiac edema. It is a prodrug of tolvaptan, [1] [2] formulated as the salt tolvaptan sodium phosphate, for intravenous administration. Tolvaptan phosphate is converted into the active drug tolvaptan in the human body following administration.
The "vaptan" drugs act by directly blocking the action of vasopressin at its receptors (V 1A, V 1B and V 2).These receptors have a variety of functions, with the V 1A and V 2 receptors are expressed peripherally and involved in the modulation of blood pressure and kidney function respectively, while the V 1A and V 1B receptors are expressed in the central nervous system.
The Cleveland Clinic says 10 to 15 grams a day is a safe amount. What is a normal blood sugar level? According to the CDC, a normal blood sugar level is below 140 mg/dL, or below 99 mg/dL if you ...
Specifically, I use their seasoning blends for one very specific thing: popcorn. It’s my favorite snack, and while I’m a traditionalist with simple melted butter and salt, once in a while I ...
Katie Holmes is setting the record straight about her daughter Suri Cruise's finances.. On Sunday, Dec. 8, Holmes, 45, shared a post on Instagram disputing a report from the Daily Mail that ...
Conivaptan hydrochloride is an off-white or a pale yellow power with a solubility of 0.25 mg/mL in water at 23 °C. The injectable formulation consists of 20 mg conivaptan hydrochloride, 0.4 g ethanol, 1.2 g propylene glycol and water. [2]
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109 S High St #100, Columbus, OH · Directions · (614) 224-4261