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This helicase is located on the X chromosome (Xq13.1-q21.1), in the pericentromeric heterochromatin and binds to heterochromatin protein 1. [31] [33] Studies have shown that ATRX plays a role in rDNA methylation and is essential for embryonic development. [35]
Gene location ; Chr. Band: Start: End: Gene location ... Probable ATP-dependent RNA helicase DDX5 also known as DEAD box protein 5 or RNA helicase p68 is an enzyme ...
79009 94213 Ensembl ENSG00000107625 ENSMUSG00000020076 UniProt Q9BQ39 Q99MJ9 RefSeq (mRNA) NM_024045 NM_053183 NM_001358819 NM_001358820 RefSeq (protein) NP_076950 NP_444413 NP_001345748 NP_001345749 Location (UCSC) Chr 10: 68.9 – 68.95 Mb Chr 10: 62.45 – 62.49 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse ATP-dependent RNA helicase DDX50 is an enzyme that in humans is encoded ...
n/a Ensembl ENSG00000184735 n/a UniProt Q86TM3 n/a RefSeq (mRNA) NM_182699 n/a RefSeq (protein) NP_874358 n/a Location (UCSC) Chr X: 23 – 23 Mb n/a PubMed search n/a Wikidata View/Edit Human DEAD-box helicase 53 is a protein that in humans is encoded by the DDX53 gene. Function This intronless gene encodes a protein which contains several domains found in members of the DEAD-box helicase ...
DEAD box proteins were first brought to attention in the late 1980s in a study that looked at a group of NTP binding sites that were similar in sequence to the eIF4A RNA helicase sequence. [4] The results of this study showed that these proteins (p68, SrmB, MSS116, vasa, PL10, mammalian eIF4A, yeast eIF4A) involved in RNA metabolism had several ...
Helicase is an enzyme which breaks hydrogen bonds between the base pairs in the middle of the DNA duplex. Its doughnut like structure wraps around DNA and separates the strands ahead of DNA synthesis. In eukaryotes, the Mcm2-7 complex acts as a helicase, though which subunits are required for helicase activity is not entirely clear. [2]
Werner syndrome ATP-dependent helicase, also known as DNA helicase, RecQ-like type 3, is an enzyme that in humans is encoded by the WRN gene. WRN is a member of the RecQ Helicase family. [ 5 ] Helicase enzymes generally unwind and separate double-stranded DNA .
1654 13205 Ensembl ENSG00000215301 ENSMUSG00000000787 UniProt O00571 Q62167 RefSeq (mRNA) NM_001193416 NM_001193417 NM_001356 NM_024005 NM_001363819 NM_010028 NM_008015 RefSeq (protein) NP_001180345 NP_001180346 NP_001347 NP_001350748 NP_034158 Location (UCSC) Chr X: 41.33 – 41.36 Mb Chr X: 13.15 – 13.16 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse ATP-dependent RNA helicase ...