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The maximum lifespans of humans, naked mole-rats, and mice are respectively c. 120, 30 and 3 years. The longer-lived species, humans and naked mole-rats, expressed DNA repair genes, including core genes in several DNA repair pathways, at a higher level than did mice.
The DNA repair transcriptomes of the liver of humans, naked mole-rats and mice were compared. [114] The maximum lifespans of humans, naked mole-rat, and mouse are respectively ~120, 30 and 3 years. The longer-lived species, humans and naked mole rats expressed DNA repair genes, including core genes in several DNA repair pathways, at a higher ...
The Middle East blind mole-rat weighs 100–200 grams (3.5–7.1 oz). It has light gray fur and four sharp teeth, two large teeth in the upper jaw and two smaller teeth in the lower jaw. It has a life span of up to 20 years and is notable for its adaptability to severe lack of oxygen. In Israel, the blind mole-rat is a major agricultural pest.
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In 2018, naked mole-rats were identified as the first mammal to defy the Gompertz–Makeham law of mortality, and achieve negligible senescence. It has been speculated, however, that this may be simply a "time-stretching" effect primarily due to their very slow (and cold-blooded and hypoxic) metabolism. [6] [7] [8]
The common mole-rat, African mole-rat, or Hottentot mole-rat, (Cryptomys hottentotus) is a burrowing rodent found in Southern Africa, in particular in the Western Cape province of South Africa. It also occurs in Eswatini, Lesotho, Malawi, Mozambique, Tanzania, Zambia, and Zimbabwe. It is a species in the subfamily Bathyerginae. [2]
Skull of a silvery mole-rat. This is a medium-sized mole-rat with soft, silky silvery-grey fur. The head is paler around the eyes, the sides of the face and the snout, and some individuals have a small white patch on the forehead. The long, slightly-curved incisors lie outside the lips. The upper parts of head and body are silvery-grey to tan ...
Mole-rat or mole rat can refer to several groups of burrowing Old World rodents: Bathyergidae, a family of about 20 hystricognath species in six genera from Africa also called blesmols. Heterocephalus glaber, the naked mole-rat. Spalacidae, a family of about 30 muroid species in six genera from Eurasia and northeast Africa, including: