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The naked mole-rat (Heterocephalus glaber), also known as the sand puppy, [6] is a burrowing rodent native to the Horn of Africa and parts of Kenya, notably in Somali regions. [1] It is closely related to the blesmols and is the only species in the genus Heterocephalus .
Rochelle Buffenstein is an American comparative biologist currently working as Research Professor at the University of Illinois Chicago.Previously, she was a senior principal investigator at Calico Life Sciences, an Alphabet, Inc. funded research and development company investigating the biology that controls aging and lifespan where she used the extraordinarily long-lived cancer resistant ...
The naked mole rat has a disproportionately long life of 30 years through efficient cellular repair mechanisms. There are numerous studies that support cellular damage, often due to a lack of somatic maintenance mechanisms, as a primary determinant for aging, and these studies have given rise to the free radical theory of aging and the DNA ...
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The Middle East blind mole-rat weighs 100–200 grams (3.5–7.1 oz). It has light gray fur and four sharp teeth, two large teeth in the upper jaw and two smaller teeth in the lower jaw. It has a life span of up to 20 years and is notable for its adaptability to severe lack of oxygen. In Israel, the blind mole-rat is a major agricultural pest.
The lesser blind mole-rat (Nannospalax leucodon) is a species of rodent in the family Spalacidae. It is found in Albania, Bosnia and Herzegovina, Bulgaria, Croatia, Greece, Hungary, North Macedonia, Moldova, Romania, Serbia, Montenegro, Turkey and Ukraine.
The DNA repair transcriptomes of the liver of humans, naked mole-rats and mice were compared. [114] The maximum lifespans of humans, naked mole-rat, and mouse are respectively ~120, 30 and 3 years. The longer-lived species, humans and naked mole rats expressed DNA repair genes, including core genes in several DNA repair pathways, at a higher ...
The sandy blind mole-rat (Spalax arenarius) is an endangered species of rodent in the family Spalacidae. It is endemic to Ukraine . [ 2 ] It was first identified by Evdokia Reshetnik in 1939.