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Spina bifida (SB; /ˌspaɪnə ˈbɪfɪdə/, [9] Latin for 'split spine') [10] is a birth defect in which there is incomplete closing of the spine and the membranes around the spinal cord during early development in pregnancy. [1] There are three main types: spina bifida occulta, meningocele and myelomeningocele. [1]
English: An ultrasound visualisation of the spine of a foetus at 21 weeks of pregnancy. The foetus is affected by open spina bifida (spina bifida cystica). In the centre of this longitudinal scan a lumbar myelomeningocele appears as dome shaped structure attached to the lumbar region of the foetal spine.
Spina bifida cystica includes meningocele and myelomeningocele. Meningocele is less severe and is characterized by herniation of the meninges, but not the spinal cord, through the opening in the spinal canal. Myelomeningocele involves herniation of the meninges as well as the spinal cord through the opening. [19] Spina bifida occulta means ...
Spina bifida is the most common defect impacting the Central Nervous System (CNS). The most common and most severe form of Spina Bifida is Myelomeningocele. Individuals with Myelomeningocele are born with an incompletely fused spine, and therefore exposing the spinal cord through an opening in the back.
The MOMS Trial was a clinical trial that studied treatment of a birth defect called myelomeningocele, which is the most severe form of spina bifida. The study looked at prenatal (before birth) and postnatal (after birth) surgery to repair this defect. The first major phase concluded that prenatal surgery had strong, long-term benefits and some ...
Spina bifida is a birth defect that affects the lowest part of the spine and occurs when a fetus's neural tube does not fully close, causing the backbone that protects the spinal cord not to form ...
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Jarcho–Levin syndrome associated with spina bifida and diastematomyelia (type I split cord malformation) 4: Duru S et al. 1999: 2: First case of 2-year-old girl, spondylocostal dysostosis with lipomyelomeningocele, and polythelia on the right side. Second case of 6-month-old girl, spondylocostal dysostosis with myelomeningocele and hydrocephalus