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Property condition assessments (PCAs) (also known as the property condition report, or PCR) are due diligence projects associated with commercial real estate.Commercial property and building inspections are important for clients seeking to know the condition of a property or real estate they may be purchasing, leasing, financing or simply maintaining.
In August 2020, an updated version of the guidelines for the digital PCR method was published to account for improvement in machinery, technologies, and techniques since the original 2013 release. Additional guideline steps were added for data analysis, while also providing a more simplified checklist table for researchers to use. [15]
The pavement condition index (PCI) is a numerical index between 0 and 100, which is used to indicate the general condition of a pavement section.The PCI is widely used in transportation civil engineering [1] and asset management, and many municipalities use it to measure the performance of their road infrastructure and their levels of service. [2]
Under ASTM E 1527-13 parameters were set forth as to who is qualified to perform Phase I ESAs. An Environmental Professional is someone with: [9] a current Professional Engineer's or Professional Geologist's license or registration from a state or U.S. territory with 3 years equivalent full-time experience; or
Computer simulations of theoretical PCR results (Electronic PCR) may be performed to assist in primer design. [ 14 ] Touchdown polymerase chain reaction or touchdown style polymerase chain reaction is a method of polymerase chain reaction by which primers will avoid amplifying nonspecific sequences.
ISO 14025 establishes the procedure for developing PCRs and the required content of a PCR, as well as requirements for comparability. [21] Sub-PCRs, or complementary-PCRs, add additional rules and guidelines for specific product sub-categories and are intended to be used in conjunction with a core PCR.
ISPE has published a series of good practice guides for the industry on several topics involved in drug manufacturing. The most well-known is The Good Automated Manufacturing Practice (GAMP) Guide for Validation of Automated Systems in Pharmaceutical Manufacture.
Second, the formerly obtained PCR products are combined together into the overlap extension PCR reaction, where the complementary overhangs bind pair-wise allowing the polymerase to extend the DNA strand. Eventually, outer primers targeting the external overhangs are used and the desired DNA product is amplified in the final PCR reaction.