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Thereafter, the otic cup closes off, creating the otic vesicle. Once formed, the otic vesicle will reside next to the neural tube medially, and on the lateral side will be paraxial mesoderm. Neural crest cells will migrate rostral and caudal to the placode. The general sequence in formation of the otic vesicle is relatively conserved across ...
The first part of the ear to develop is the inner ear, [19] which begins to form from the ectoderm around the embryo's 22nd day, [18] derived from two thickenings called otic placodes on either side of the head. Each otic placode recedes below the ectoderm, forms an otic pit and then an otic vesicle. [20]
The cochlear duct develops from the ventral otic vesicle (otocyst). [3] It grows slightly flattened between the middle and outside of the body. [3] This development may be regulated by the genes EYA1, SIX1, GATA3, and TBX1. [3] The organ of Corti develops inside the cochlear duct. [4]
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The otic vesicles then form ventral and dorsal components. The ventral component forms the saccule and the cochlear duct . In the sixth week of development the cochlear duct emerges and penetrates the surrounding mesenchyme , travelling in a spiral shape until it forms 2.5 turns by the end of the eighth week.
The ear, including both the vestibular system and the auditory system, develops from the otic placode beginning the third week of development. During the fourth week, the otic placode invaginates into the mesenchyme adjacent to the rhombencephalon to form the otic pit, which then pinches off from the surface ectoderm to form the otic vesicle. [1]
In embryology, the neural plate is a key developmental structure that serves as the basis for the nervous system.Cranial to the primitive node of the embryonic primitive streak, ectodermal tissue thickens and flattens to become the neural plate.
The optic vesicle will then induce the ectoderm that thickens (lens placode) and further invaginates to a point that detaches from the ectoderm and forms a neurogenic placode by itself. The lens placode is affected by the chordamesoderm making it invaginate and forms the optic cup composed by an inner layer of the neural retina and outer layer ...