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Vitamin D deficiency or hypovitaminosis D is a vitamin D level that is below normal. It most commonly occurs in people when they have inadequate exposure to sunlight , particularly sunlight with adequate ultraviolet B rays (UVB).
Vitamin D deficiency Usually asymptomatic, causes reduce bone density ( osteomalacia ), rickets, myopathy, and is associated with the development of schizophrenia . It is typically diagnosed by measuring the concentration of the 25-hydroxyvitamin D (25(OH)D) in plasma, which is the most accurate measure of stores of vitamin D in the body.
Many multivitamin formulas contain vitamin C, B 1, B 2, B 3, B 5, B 6, B 7, B 9, B 12, A, E, D 2 (or D 3), K, potassium, iodine, selenium, borate, zinc, calcium, magnesium, manganese, molybdenum, beta carotene, and/or iron. Multivitamins are typically available in a variety of formulas based on age and sex, or (as in prenatal vitamins) based on ...
Specifically, consuming 2,000 IU (international units) a day of supplemental vitamin D3 without calcium over the course of more than five years did not reduce total fractures, hip, wrist or pelvic ...
The prevalence of vitamin K deficiency varies by geographic region. For infants in the United States, vitamin K 1 deficiency without bleeding may occur in as many as 50% of infants younger than 5 days old, with the classic hemorrhagic disease occurring in 0.25-1.7% of infants. [2]
Calcifediol is the precursor for calcitriol, the active form of vitamin D. [3] [4] It is synthesized in the liver, by hydroxylation of cholecalciferol (vitamin D 3) at the 25-position. [3] This enzymatic 25-hydroxylase reaction is mostly due to the actions of CYP2R1 , present in microsomes , although other enzymes such as mitochondrial CYP27A1 ...
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