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Antibiotics by mouth and by intravenous appear similar. [32] [33] Due to insufficient evidence it is unclear what the best antibiotic treatment is for osteomyelitis in people with sickle cell disease as of 2019. [34] Initial first-line antibiotic choice is determined by the patient's history and regional differences in common infective organisms.
Antibiotic choice should be guided by deep tissue culture, severity of the infection, presence or absence of osteomyelitis, prior antibiotic treatment, and previous or current MRSA infection. [17] Wounds without confirmed infection should not be treated with antibiotics, nor should be sent for culture.
Flucloxacillin, also known as floxacillin, is an antibiotic used to treat skin infections, external ear infections, infections of leg ulcers, diabetic foot infections, and infection of bone. [6] It may be used together with other medications to treat pneumonia, and endocarditis. [6]
The veterinary uses of clindamycin are quite similar to its human indications, and include treatment of osteomyelitis, [74] skin infections, and toxoplasmosis, for which it is the preferred drug in dogs and cats. [75] They can be used both by mouth and topically. [62] A disadvantage is that bacterial resistance can develop fairly quickly. [62]
Dicloxacillin is a narrow-spectrum β-lactam antibiotic of the penicillin class. [1] It is used to treat infections caused by susceptible (non-resistant) Gram-positive bacteria. [1] It is active against beta-lactamase-producing organisms such as Staphylococcus aureus, which would otherwise be resistant to most penicillins.
Most diabetic foot infections (DFIs) require treatment with systemic antibiotics. The choice of the initial antibiotic treatment depends on several factors such as the severity of the infection, whether the patient has received another antibiotic treatment for it, and whether the infection has been caused by a micro-organism that is known to be ...
Surgery is the main treatment, often combined with antibiotics. The prognosis is generally favorable, with minimal risk of lasting disability or recurrence. Brodie abscess is responsible for 2.5%-42% of primary bone infections. It is named after Sir Benjamin Collins Brodie, 1st Baronet, who initially described the condition in the 1830s.
Ciprofloxacin is a fluoroquinolone antibiotic used to treat a number of bacterial infections. [5] This includes bone and joint infections, intra-abdominal infections, certain types of infectious diarrhea, respiratory tract infections, skin infections, typhoid fever, and urinary tract infections, among others. [5]