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AIDS-defining clinical conditions (also known as AIDS-defining illnesses or AIDS-defining diseases) is the list of diseases published by the Centers for Disease Control and Prevention (CDC) that are associated with AIDS and used worldwide as a guideline for AIDS diagnosis.
Considerable variation exists in the relative risk of death following different AIDS defining clinical conditions. According to the US CDC definition, one has AIDS if he/she is infected with HIV and present with one of the following: A CD4+ T-cell count below 200 cells/μl (or a CD4+ T-cell percentage of total lymphocytes of less than 14%) OR
(This is the interim African Region version for persons aged 15 years or more who have had a positive HIV antibody test or other laboratory evidence of HIV infection) (The United Nations defines adolescents as persons aged 10−19 years but for surveillance purposes, the category of adults and adolescents comprises people aged 15 years and over)
Most of these conditions are opportunistic infections that are easily treated in healthy people. The staging system is different for adults and adolescents and children. [2] Stage I: HIV disease is asymptomatic and not categorized as AIDS. Stage II: include minor mucocutaneous manifestations and recurrent upper respiratory tract infections.
Stage 3: CD4 count ≤ 200 cells/μL or AIDS-defining conditions; Unknown: if insufficient information is available to make any of the above classifications. For surveillance purposes, the AIDS diagnosis still stands even if, after treatment, the CD4 + T cell count rises to above 200 per μL of blood or other AIDS-defining illnesses are cured. [29]
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Conditions where confirmatory diagnostic testing is necessary: Chronic HIV-associated lung disease including bronchiectasis; Lymphoid interstitial pneumonitis (LIP) Unexplained anaemia (<80g/L), and or neutropenia (<1000/μL) and or thrombocytopenia (<50 000/μL) for more than one month
By Leah Douglas and Julie Steenhuysen (Reuters) -California's public health department reported a possible case of bird flu in a child with mild respiratory symptoms on Tuesday, but said there was ...
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