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Meconium aspiration syndrome (MAS), also known as neonatal aspiration of meconium, is a medical condition affecting newborn infants. It describes the spectrum of disorders and pathophysiology of newborns born in meconium-stained amniotic fluid (MSAF) and have meconium within their lungs. Therefore, MAS has a wide range of severity depending on ...
The syndrome develops in about 20% of human pregnancies continuing past the expected delivery date. [3] Features of post-maturity syndrome include oligohydramnios (a deficiency of amniotic fluid); [4] meconium aspiration (breathing meconium in the amniotic fluid); and macrosomia (being overly large).
Perinatal asphyxia (also known as neonatal asphyxia or birth asphyxia) is the medical condition resulting from deprivation of oxygen to a newborn infant that lasts long enough during the birth process to cause physical harm, usually to the brain.
It is associated with complications such as cord compression, abnormal heart rate, fetal acidosis, and meconium amniotic fluid. [10] Meconium aspiration syndrome – Respiratory compromise secondary to meconium present in infant's lungs. [11] Macrosomia – Excessive birth weight, estimated fetal weight of ≥ 4.5 kg.
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Intrauterine hypoxia can be attributed to maternal, placental, or fetal conditions. [12] Kingdom and Kaufmann classifies three categories for the origin of fetal hypoxia: 1) pre-placental (both mother and fetus are hypoxic), 2) utero-placental (mother is normal but placenta and fetus is hypoxic), 3) post-placental (only fetus is hypoxic).
Neelam Kler is an Indian neonatologist, known for her pioneering work on neonatal intensive care and ventilation. [1] She is credited with developing neonatal care to better the survival rate of extremely tiny preterm babies (less than 1000 grams) to 90 percent. [2]
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