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Hypertrophic cardiomyopathy (HCM, or HOCM when obstructive) is a condition in which muscle tissues of the heart become thickened without an obvious cause. [8] The parts of the heart most commonly affected are the interventricular septum and the ventricles. [10]
Hypertrophic cardiomyopathy. Hypertrophic cardiomyopathy develops when the walls of your left ventricle become thicker than normal. It’s the most common cardiomyopathy caused by inherited genes.
Inferior left ventricle wall scar, short axis echocardiography view. Myocardial scarring is the accumulation of fibrous tissue resulting after some form of trauma to the cardiac tissue. [1] [2] Fibrosis is the formation of excess tissue in replacement of necrotic or extensively damaged tissue.
Hypertrophic cardiomyopathy remains a shifty and unpredictable foe. But experts say they’ve learned to roll with its punches. “Things have moved in the direction we hoped,” Maron says.
Hypertrophic cardiomyopathy affects about 1 in 500 people while dilated cardiomyopathy affects 1 in 2,500. [ 3 ] [ 10 ] They resulted in 354,000 deaths up from 294,000 in 1990. [ 7 ] [ 11 ] Arrhythmogenic right ventricular dysplasia is more common in young people.
Athlete's heart is not the cause of sudden cardiac death during or shortly after a workout, which mainly occurs due to hypertrophic cardiomyopathy and arrhythmogenic cardiomyopathy (ARVC), two genetic disorders. Although a link between intensive exercise and exercise-induced arrhythmogenic right ventricular cardiomyopathy exists. [3] [6]
The underlying commonality in these disease states is an increase in pressures that the ventricles experience. For example, in tetralogy of Fallot, the right ventricle is exposed to the high pressures of the left heart due to a defect in the septum; as a result the right ventricle undergoes hypertrophy to compensate for these increased pressures.
[15] [16] [17] Tissue Doppler technology, the alternative method for strain rate imaging to speckle tracking technology, requires achieving sufficient parallel orientation between the direction of motion and the ultrasound beam. Its use has remained limited due to angle dependency, substantial intraobserver and interobserver variability and ...
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