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Etoposide interferes with grapefruit, orange, and apple juices. [12] Fexofenadine (Allegra) concentrations are decreased rather than increased as is the case with most grapefruit–drug interactions. [73] [74] Fluvoxamine (Luvox, Faverin, Fevarin and Dumyrox) [75]
Blood pressure drugs aren't the only commonly prescribed medications that grapefruit juice can mess with — they also include anticoagulants that help prevent blood clots, organ-transplant ...
Grapefruit and grapefruit juice have been found to interact with numerous drugs, in many cases resulting in adverse effects. [4] This happens in two ways: one is that grapefruit can block an enzyme which metabolizes medication, [5] and if the drug is not metabolized, then the level of the drug in the blood can become too high, leading to an adverse effect. [5]
In pharmaceutical sciences, drug interactions occur when a drug's mechanism of action is affected by the concomitant administration of substances such as foods, beverages, or other drugs. A popular example of drug–food interaction is the effect of grapefruit on the metabolism of drugs .
Grapefruit–drug interactions are common, as the juice contains furanocoumarins that interfere with the metabolism of many drugs. This can prolong and intensify the effects of those drugs, leading to multiple side-effects such as abnormal heart rhythms, bleeding inside the stomach, low blood pressure, difficulty breathing, and dizziness.
Here is a list of the products recalled since Nov. 1, according to the U.S. Food and Drug Administration website.
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2012: As of 2 November 2012 in the New England Compounding Center meningitis outbreak, 753 cases of fungal infection occurred with 64 deaths due to contaminated injectable medication. 2012: 2012 Pakistan fake medicine crisis; 2017: medical cannabis in California found to contain dangerous bacteria and fungi, causing at least one fatality. [19]