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Drug-induced hepatitis, from TB treatment, has a mortality rate of around 5%. [53] Three drugs can induce hepatitis: PZA, INH, and RMP (in decreasing order of frequency). [54] It is not possible to distinguish between these three causes based purely on signs and symptoms. Test dosing must be carried out to determine which drug is responsible ...
The symptoms of abdominal tuberculosis depends on the sites of involvement. The most common symptoms and signs of abdominal tuberculosis are abdominal pain, ascites and intestinal obstruction. Other clinical features are fever, altered bowel habits, loss of weight and a feeling of lump in the abdomen. [ 5 ]
Diagnosing active tuberculosis based only on signs and symptoms is difficult, [99] as is diagnosing the disease in those who have a weakened immune system. [100] A diagnosis of TB should, however, be considered in those with signs of lung disease or constitutional symptoms lasting longer than two weeks. [100]
Chronic liver disease takes several years to develop and the condition may not be recognised unless there is clinical awareness of subtle signs and investigation of abnormal liver function tests. Testing for chronic liver disease involves blood tests, imaging including ultrasound, and a biopsy of the liver. The liver biopsy is a simple ...
Drug-induced liver injury (DILI) is a cause of acute and chronic liver disease caused specifically by medications and the most common reason for a drug to be withdrawn from the market after approval. The liver plays a central role in transforming and clearing chemicals and is susceptible to the toxicity from these agents.
If the fatty liver disease has progressed to a more advanced stage like NASH or cirrhosis, the symptoms can be more obvious and severe, says Dr. Robbins. Symptoms of advanced liver disease and ...
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