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Testosterone is absorbed through the oral mucosa and avoids the first-pass metabolism in the liver which is the cause of many of the adverse effects of oral testosterone undecanoate. The lozenges can cause gum irritation, taste changes, and headache but most side effects diminish after two weeks.
In addition to the lack of research showing the benefits of testosterone for women, taking the hormone can also come with side effects, including unwanted hair growth, acne, liver damage, hair ...
Health risks can be produced by long-term use or excessive doses of AAS. [2] [3] These effects include harmful changes in cholesterol levels (increased low-density lipoprotein and decreased high-density lipoprotein), acne, high blood pressure, liver damage (mainly with most oral AAS), and left ventricular hypertrophy. [4]
[122] [126] High doses or levels of AAS, including testosterone, can cause polycythemia—high red blood cell and/or hemoglobin levels that increase the risk of stroke—as an adverse effect. [121] [122] Conversely, whether via castration, NSAA monotherapy, or CAB, decreased erythropoiesis resulting in mild anemia is a common side effect of ADT ...
Testosterone replacement therapy (TRT) can also cause DHT levels to increase. "You can imagine with uninhibited increased T levels, your body combats that by increasing the level of DHT," says ...
Injuries to the testicles and cancer treatments like chemotherapy and radiation can cause low testosterone levels. So can some medications (including hormones used to treat prostate cancer), aging ...
High levels of testosterone are also achieved with a 60 mg dose of oral testosterone in men with liver cirrhosis. [2] These findings are attributed to induction of liver enzymes by testosterone and consequent activation of its own metabolism. [2] [27] Substitution dosages of oral testosterone in men are in the range of 400 to 800 mg/day.
“Unless this is clarified in future research, it is uncertain whether low testosterone causes cardiovascular disease and it would be unwise and potentially dangerous to assume that treatment of ...