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The male hormone, testosterone, is produced in limited quantities following treatment with Zeuterin, but after two years, testosterone production is similar to that in untreated dogs. [1] The continuing presence of testosterone means that, unlike surgical castration, chemical castration does not remove the risk of testosterone-associated ...
Reaction at the injection site if you use short-acting testosterone injections. Allergic reaction if you use long-acting injections. Pain and soreness at the injection site. Infections if you use ...
The first long-acting (depot) injections were antipsychotics fluphenazine and haloperidol. [2] The concept of a depot injection arose before 1950, and originally was used to describe antibiotic injections that lasted longer to allow for less frequent administration.
However, it has been estimated that for every vaccine injected intramuscularly, 20 injections are given to administer drugs or other therapy. [6] This can include medications such as antibiotics, immunoglobulin, and hormones such as testosterone and medroxyprogesterone. [5]
Testosterone can be taken by a variety of different routes of administration. [2] [3] These include oral, buccal, sublingual, intranasal, transdermal (gels, creams, patches, solutions), vaginal (creams, gels, suppositories), rectal (suppositories), by intramuscular or subcutaneous injection (in oil solutions or aqueous suspensions), and as a subcutaneous implant.
A formulation of injected testosterone available in Europe and the US, testosterone undecanoate (Nebido, Aveed) [21] [22] provides significantly improved testosterone delivery with far less variation outside the eugonadal range than other formulations with injections required only four times yearly. However, each quarterly dose requires an ...
When given as long-acting implants, these cause “medical castration,” that is, the complete suppression of reproductive activity and the suppression of sex steroids. They have been shown to be effective in both dogs and cats. Compounds that bind and block the GnRH receptor can also cause suppression of fertility and sex steroids.
Testosterone enanthate is used primarily in androgen replacement therapy. [4] [15] It is the most widely used form of testosterone in androgen replacement therapy. [4]The medication is specifically approved, in the United States, for the treatment of hypogonadism in men, delayed puberty in boys, and breast cancer in women. [16]