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2. Tizanidine - Wikipedia

   en.wikipedia.org/wiki/Tizanidine

   Tizanidine is a derivative of 2,1,3-benzothiadiazole and its first published synthesis was reported in a patent. [17] The 5-chloro-2,1,3-benzothiadiazol-4-amine intermediate was a known compound, produced in three steps from 4-chlorophenylenediamine as shown. [ 18 ]

3. Review links 3 potentially-blinding eye conditions to GLP-1 ...

   www.aol.com/review-links-3-potentially-blinding...

   A new review reports that nine people taking semaglutide and tirzepatide — the active ingredient in GLP-1 medications — experienced vision issues, including three potentially blinding eye ...

4. FDA approves first new type of pain medication in 25 years - AOL

   www.aol.com/news/fda-approves-first-type-pain...

   It will be sold under the brand name Journavx. ... followed by 50 milligrams every 12 hours. ... Vertex said that it has set a wholesale cost of $15.50 per 50-mg pill but that patient assistance ...

5. Chlorzoxazone - Wikipedia

   en.wikipedia.org/wiki/Chlorzoxazone

   [medical citation needed] Elucidation of the exact mechanism of action is ongoing but there is limited study due to the existence of more effective, safe muscle relaxants (e.g., diazepam, cyclobenzaprine, tizanidine), greatly limiting the potential benefit of identifying novel compounds which share chlorzoxazone's mechanism of action.

6. FDA approves new pain medication as an alternative to opioids ...

   www.aol.com/news/fda-approves-pain-medication...

   The medication will be sold under the brand name Journavx for $15.50 per pill, according to Vertex Pharmaceuticals, the company that developed the new drug.

7. Opipramol - Wikipedia

   en.wikipedia.org/wiki/Opipramol

   After single oral administration of 100 mg the maximum plasma concentration is reached after 3 hours and amounts to 33.2 ng/mL. [3] Therapeutic concentrations of opipramol range from 140 to 550 nmol/L. [ 26 ] The plasma protein binding amounts to approximately 91% and the volume of distribution is approximately 10 L/kg. [ 3 ]

8. Border Patrol agent whose death is tied to cultlike Zizians ...

   www.aol.com/border-patrol-agent-whose-death...

   A U.S. Border Patrol agent whose killing in Vermont during a traffic stop near the Canadian border has been tied to a cultlike group is scheduled to be buried with full military honors Saturday at ...

9. Tetrazepam - Wikipedia

   en.wikipedia.org/wiki/Tetrazepam

   The indicated adult dose for muscle spasm is 25 mg to 150 mg per day, increased if necessary to a maximum of 300 mg per day, in divided doses. Tetrazepam is not generally recommended for use in children, except on the advice of a specialist. Tetrazepam is only available in one strength and formulation, 50 mg tablets.