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Martínez López de Letona J. (2007). La historia natural de la enfermedad como fuente esencial para la formulación del pronóstico (PDF). Madrid: HM. ISBN 978-84-612-7199-3. Archived from the original (PDF) on 2013-08-18. Bhopal, R. (2008). Concepts of Epidemiology. Integrating the ideas, theories, principles and methods of epidemiology (2nd ...
This is a timeline of influenza, briefly describing major events such as outbreaks, epidemics, pandemics, discoveries and developments of vaccines.In addition to specific year/period-related events, there is the seasonal flu that kills between 250,000 and 500,000 people every year and has claimed between 340 million and 1 billion human lives throughout history.
The natural hosts of influenza viruses are pigs and birds, although it has probably infected humans since antiquity. [245] The virus can cause mild to severe epizootics in wild and domesticated animals. [246] Many species of wild birds migrate and this has spread influenza across the continents throughout the ages.
Influenza A/H1N1: 17–100 million 1–5.4% of global population [4] 1918–1920 Worldwide 2 Plague of Justinian: Bubonic plague 15–100 million 25–60% of European population [5] 541–549 North Africa, Europe, and Western Asia 3 HIV/AIDS pandemic: HIV/AIDS: 44 million (as of 2025) – 1981–present [6] Worldwide 4 Black Death: Bubonic plague
Francisco Hernández de Toledo, a Spanish physician, insisted on using the Nahuatl word when describing the disease to correspondents in the Old World. [19] In 1970, a historian named Germaine Somolinos d'Ardois looked systematically at the proposed explanations, including hemorrhagic influenza, leptospirosis , malaria , typhus, typhoid , and ...
The sequences of the polymerase proteins (PA, PB1, and PB2) of the 1918 virus and subsequent human viruses differ by only 10 amino acids from the avian influenza viruses. Viruses with 7 of the 10 amino acids in the human influenza locations have already been identified in currently circulating H5N1. This has led some researchers to suggest that ...
[12] [23] Influenza D virus causes an influenza-like illness in pigs but its impact in its natural reservoir, cattle, is relatively unknown. It may cause respiratory disease resembling human influenza on its own, or it may be part of a bovine respiratory disease (BRD) complex with other pathogens during co-infection.
Between the fall of 1789 and the spring of 1790, influenza occurred extensively throughout the United States and North America more broadly. First reported in the southern United States in September, it spread throughout the northern states in October and November, appeared about the same time in the West Indies, and reached as far north as Nova Scotia before the end of 1789.