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Space-filling model of the PTEN protein (blue) complexed with tartaric acid (brown) [5] Phosphatase and tensin homolog (PTEN) is a phosphatase in humans and is encoded by the PTEN gene. [6] Mutations of this gene are a step in the development of many cancers, specifically glioblastoma, lung cancer, breast cancer, and prostate cancer.
PTEN also refers to a member of the class, phosphatase and tensin homolog. [ citation needed ] This enzyme participates in 10 metabolic pathways : inositol phosphate metabolism , phosphatidylinositol signaling system , p53 signaling pathway , focal adhesion , tight junction , endometrial cancer , glioma , prostate cancer , melanoma , and small ...
Nevertheless, phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase, the well-studied tumor suppressor that is better known as PTEN, gets its name from homology with PTPs and tensin 1. [6] More detailed structure comparisons have revealed that tensins 1-3, PTEN , auxilin [ 5 ] and other proteins in animals, plants and fungi comprise a PTP-C2 ...
Crystallographic structure of human phosphatase and tensin homolog (PTEN). The active site of the blue N-terminal phosphatase domain is shown in yellow. The C-terminal C2 domain is shown in red.
In plants, in addition to the action of dry abiotic factors, high temperature, ... (Rb), and phosphatase and tensin homolog (PTEN). [61] Carcinogenesis
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As President Donald Trump moved last month to free the people who stormed the U.S. Capitol, his newly appointed top prosecutor in Washington put his name on a request that a judge drop charges ...
PTEN may mean: Prime Time Entertainment Network PTEN (gene) , a human tumour suppressor gene on chromosome 10 (and its protein: phosphatase and tensin homolog)
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related to: pten phosphatase and tensin homolog in plants