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This is a list of the largest known epidemics and pandemics caused by an infectious disease in humans. Widespread non-communicable diseases such as cardiovascular disease and cancer are not included. An epidemic is the rapid spread of disease to a large number of people in a given population within a short period of time; in meningococcal ...
In the first half of the 17th century, the Great Plague of Milan claimed some 1.7 million victims in Italy, or about 14% of the population. [47] In 1656, the plague killed about half of Naples' 300,000 inhabitants. [48] More than 1.25 million deaths resulted from the extreme incidence of plague in 17th-century Spain. [49]
25,000,000 – 50,000,000 (estimated) The Black Death was a bubonic plague pandemic occurring in Europe from 1346 to 1353. It was one of the most fatal pandemics in human history; as many as 50 million people [2] perished, perhaps 50% of Europe's 14th century population. [3] The disease is caused by the bacterium Yersinia pestis and spread by ...
One of the worst plagues in history, the Black Death arrived on the shores of Europe in 1347. Five years later, around 25 to 50 million people were dead across the continent.
The plague is considered the likely cause of the Black Death that swept through Asia, Europe, and Africa in the 14th century and killed an estimated 50 million people, [1] [10] including about 25% to 60% of the European population. [1] [11] Because the plague killed so many of the working population, wages rose due to the demand for labor. [11]
The second plague pandemic was a major series of epidemics of plague that started with the Black Death, which reached medieval Europe in 1346 and killed up to half of the population of Eurasia in the next four years. It followed the first plague pandemic that began in the 6th century with the Plague of Justinian, but had ended in the 8th ...
Symptoms of the Bubonic Plague included painful and enlarged or swollen lymph nodes, headaches, chills, fatigue, vomiting, and fevers, and within 3 to 5 days, 80% of the victims would be dead. [1] Historians estimate that it reduced the total world population from 475 million to between 350 and 375 million.
A natural reservoir of plague is located in western Yunnan and is an ongoing health risk today. The third pandemic of plague originated in this area after a rapid influx of Han Chinese to exploit the demand for minerals, primarily copper, in the latter half of the 19th century. [50] By 1850, the population had exploded to over 7,000,000 people.