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Biguanide (/ b aɪ ˈ ɡ w ɒ n aɪ d /) is the organic compound with the formula HN(C(NH)NH 2) 2. It is a colorless solid that dissolves in water to give a highly basic solution. It is a colorless solid that dissolves in water to give a highly basic solution.
The Craig plot, named after Paul N. Craig, is a plot of two substituent parameters (e.g. Hansch-Fujita π constant and sigma constant) used in rational drug design. [1] Two most used forms of a Craig plot are plotting the sigma constants of the Hammett equation versus hydrophobicity; plotting the steric terms of the Taft equation against ...
(However, PE only dissolves at temperatures well above 100 °C.) Poly(styrene) has a solubility parameter of 9.1 cal 1/2 cm −3/2, and thus ethyl acetate is likely to be a good solvent. Nylon 6,6 has a solubility parameter of 13.7 cal 1/2 cm −3/2, and ethanol is likely to be the best solvent of those tabulated. However, the latter is polar ...
meta-Chlorophenylbiguanide (1-(3-Chlorophenylbiguanide, m-CPBG) is an allosteric agonist and modulator of the 5-HT 3 receptor [1] [2] [3] and an antagonist of the α 2A-adrenergic receptor. [4] It has anxiogenic , emetic and hypothermic effects in animal studies.
Structure of chlorhexidine, a bisbiguanide antiseptic.. Bisbiguanides are a class of chemically related compounds known for their bactericidal properties. Generally considered to be of the generic formula: R 1 R 2 N.C(:NR 6)NH.C(:NH)NH.CH 2 X--(CH 2) 3 NH.C(:NH)NH.C(:NR 7)NR 3 R 4 V. [1] These compounds include the antiseptics chlorhexidine and alexidine.
This π-complex is not found in the H 3 O + (H 2 O) 6. The Beckmann rearrangement scheme for acetophenone oxime under oxonium–acetic acid complex and hydronium–water complex. With the cyclohexanone-oxime, the relief of ring strain results in a third reaction mechanism, leading directly to the protonated caprolactam in a single concerted ...
Succinimide is an organic compound with the formula (CH 2) 2 (CO) 2 NH. This white solid is used in a variety of organic syntheses, as well as in some industrial silver plating processes. The compound is classified as a cyclic imide. It may be prepared by thermal decomposition of ammonium succinate. [4]
Thiourea (/ ˌ θ aɪ. oʊ j ʊəˈr iː. ə,-ˈ jʊər i-/) [2] [3]}} is an organosulfur compound with the formula SC(NH 2) 2 and the structure H 2 N−C(=S)−NH 2. It is structurally similar to urea (H 2 N−C(=O)−NH 2), with the oxygen atom replaced by sulfur atom (as implied by the thio-prefix). The properties of urea and thiourea differ ...