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The main reason for exhalation is to rid the body of carbon dioxide, which is the waste product of gas exchange in humans. Air is brought into the lungs through inhalation. Diffusion in the alveoli allows for the exchange of O 2 into the pulmonary capillaries and the removal of CO 2 and other gases from the pulmonary capillaries to be exhaled ...
Almost any type of lung tumor or lung cancer can compress the alveoli and reduce gas exchange capacity. In some cases the tumor will fill the alveoli. [33] Cavitary pneumonia is a process in which the alveoli are destroyed and produce a cavity. As the alveoli are destroyed, the surface area for gas exchange to occur becomes reduced.
The alveoli are the dead end terminals of the "tree", meaning that any air that enters them has to exit via the same route. A system such as this creates dead space, a volume of air (about 150 ml in the adult human) that fills the airways after exhalation and is breathed back into the alveoli before environmental air reaches them.
The alveoli are tiny air sacs in the lungs where gas exchange takes place. The mean number of alveoli in a human lung is 480 million. [11] When the diaphragm contracts, a negative pressure is generated in the thorax and air rushes in to fill the cavity. When that happens, these sacs fill with air, making the lung expand.
The process of breathing does not fill the alveoli with atmospheric air during each inhalation (about 350 ml per breath), but the inhaled air is carefully diluted and thoroughly mixed with a large volume of gas (about 2.5 liters in adult humans) known as the functional residual capacity which remains in the lungs after each exhalation, and ...
The alveoli continue to form into early adulthood, and their ability to form when necessary is seen in the regeneration of the lung. [64] [65] Alveolar septa have a double capillary network instead of the single network of the developed lung. Only after the maturation of the capillary network can the lung enter a normal phase of growth.
Each respiratory bronchiole supplies the alveoli held in each acinus accompanied by a pulmonary artery branch. The pulmonary lobule is the portion of the lung ventilated by one bronchiole. Bronchioles are approximately 1 mm or less in diameter and their walls consist of ciliated cuboidal epithelium and a layer of smooth muscle .
The alveolar type II epithelial cells are more resistant to damage, so after an insult to the alveoli, most of the damage will occur to the alveolar type I epithelial cells. [5] Left side demonstrate the structure of a normal alveolus including the difference between type I and type II alveolar epithelial cells.