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  2. Empagliflozin - Wikipedia

    en.wikipedia.org/wiki/Empagliflozin

    It is indicated in adults for the treatment of symptomatic chronic heart failure; [13] and it is indicated in adults for the treatment of chronic kidney disease. [ 13 ] Empagliflozin lowers risk of hospitalization and death in people with reduced heart function, when added to standard heart failure treatment with or without type 2 diabetes.

  3. SGLT2 inhibitor - Wikipedia

    en.wikipedia.org/wiki/SGLT2_inhibitor

    Sotagliflozin (Inpefa) is a dual SGLT1/SGLT2 inhibitor approved by the US Food and Drug Administration (FDA) in May 2023, to reduce the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visit in adults with heart failure or type 2 diabetes, chronic kidney disease, and other cardiovascular risk factors ...

  4. Empagliflozin/linagliptin/metformin - Wikipedia

    en.wikipedia.org/wiki/Empagliflozin/linagliptin/...

    To reduce the risk of developing ketoacidosis (a serious condition where the body produces high levels of blood acids called ketones) after surgery, the FDA has approved changes to the prescribing information for SGLT2 inhibitor diabetes medications, recommending they be temporarily stopped before scheduled surgery.

  5. Lilly, Boehringer say Jardiance slows kidney disease ... - AOL

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  6. Lilly, Boehringer say Jardiance slows kidney disease ... - AOL

    www.aol.com/news/lilly-boehringer-jardiance...

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  7. Eli Lilly, Boehringer Share Jardiance Data In Heart ... - AOL

    www.aol.com/news/eli-lilly-boehringer-share...

    In the trial, Jardiance cut the combined risk of cardiovascular death or hospitalization from heart failure in HFpEF patients with or without diabetes. At the 26-month mark, 13.8% of Jardiance ...

  8. Area under the curve (pharmacokinetics) - Wikipedia

    en.wikipedia.org/wiki/Area_under_the_curve...

    It was proposed to be used instead of AUC in animal-to-human dose translation, as computer simulation shows that it could cope better with half-life and dosing schedule variations than AUC. This is an example of a PK/PD model, which combines pharmacokinetics and pharmacodynamics. [13]

  9. Lilly's (LLY) Jardiance Heart Failure Study Meets Main Goal - AOL

    www.aol.com/news/lillys-lly-jardiance-heart...

    Lilly's (LLY) Jardiance significantly reduces the risk of the composite of cardiovascular death or hospitalization for heart failure in patients with heart failure with preserved ejection fraction.

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