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The first historical achievement in anesthesia occurred around 4000 BC in ancient Mesopotamia. [5] [10] [32] [33] [34] This was the advent of ethanol (commonly known as drinking alcohol), the first general anaesthetic agent.
General anaesthesia is usually performed in an operating theatre to allow surgical procedures that would otherwise be intolerably painful for a patient, or in an intensive care unit or emergency department to facilitate endotracheal intubation and mechanical ventilation in critically ill patients. Depending on the procedure, general anaesthesia ...
Anesthesia is a combination of the endpoints (discussed above) that are reached by drugs acting on different but overlapping sites in the central nervous system. General anesthesia (as opposed to sedation or regional anesthesia) has three main goals: lack of movement , unconsciousness, and blunting of the stress response. In the early days of ...
The Meyer-Overton correlation for anaesthetics. A nonspecific mechanism of general anaesthetic action was first proposed by Emil Harless and Ernst von Bibra in 1847. [9] They suggested that general anaesthetics may act by dissolving in the fatty fraction of brain cells and removing fatty constituents from them, thus changing activity of brain cells and inducing anaesthesia.
William Thomas Green Morton and the discovery of anesthesia]. Schweizerische Medizinische Wochenschrift (in German). 126 (47): 2040– 2. PMID 8984612. Pavlovskiĭ L. N. (2005). "Dentist William Morton is a founder of general anesthesia" [Dentist William Morton is a founder of general anesthesia]. Likars'ka Sprava (in Russian) (1– 2): 111– 5.
To determine the depth of anesthesia, the anesthetist relies on a series of physical signs of the patient. In 1847, John Snow (1813–1858) [1] and Francis Plomley [2] attempted to describe various stages of general anesthesia, but Guedel in 1937 described a detailed system which was generally accepted. [3] [4] [5]
Anesthesiology, anaesthesiology or anaesthesia is the medical specialty concerned with the total perioperative care of patients before, during and after surgery. [1] It encompasses anesthesia, intensive care medicine, critical emergency medicine, and pain medicine. [2]
This account also credited Bian Que with using general anaesthesia which would place it far before Hua Tuo, but the source in Liezi is questioned and the author may have been compiling stories from other works. [40] Nonetheless, it establishes the concept of heart transplantation back to around 300 CE.