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Smoking exposes delicate cells inside the lungs directly to these compounds. This causes mutations in the DNA of the cells, which leads to cancer. According to the World Health Organization's report, "Tobacco Smoke and Involuntary Smoking", 80 percent of all cases of lung cancer are attributable to smoking.
This is an accepted version of this page This is the latest accepted revision, reviewed on 6 February 2025. Circumstances, mechanisms, and factors of tobacco consumption on human health "Health effects of smoking" and "Dangers of smoking" redirect here. For cannabis, see Effects of cannabis. For smoking crack cocaine, see Crack cocaine § Health issues. "Smoking and health" redirects here. For ...
Burning changes the properties of chemicals. Burning creates additional toxic compounds, including carcinogens. [6] According to the U.S. National Cancer Institute: "Of the more than 7,000 chemicals in tobacco smoke, at least 250 are known to be harmful, including hydrogen cyanide, carbon monoxide, and ammonia. Among the 250 known harmful ...
It is added to gum and hard lozenges used for nicotine replacement therapy in smoking cessation, such as in the Nicorette range of products. The use of the polymer as a delivery system maximizes the amount of nicotine released and absorbed by the oral mucosa . 80 to 90 percent of the nicotine released from the gum is absorbed by the mouth.
The health effects of tobacco had been debated by users, medical experts, and governments alike since its introduction to European culture. [1] Hard evidence for the ill effects of smoking became apparent with the results of several long-term studies conducted in the early to middle twentieth century, such as the epidemiology studies of Richard Doll and pathology studies of Oscar Auerbach.
The consumption of tobacco products and its harmful effects affect both smokers and non-smokers, [9] and is a major risk factor for six of the eight leading causes of deaths in the world, including respiratory diseases, cardiovascular diseases, cerebrovascular diseases, periodontal diseases, teeth decay and loss, over 20 different types or subtypes of cancers, strokes, several debilitating ...
Continued use of nicotine may result in harmful effects to women's brains because it restricts estrogen signaling. [24] This could lead to making the brain more vulnerable to ischemia . [ 24 ] A 2015 review concluded that "Nicotine acts as a gateway drug on the brain, and this effect is likely to occur whether the exposure is from smoking ...
Smoking is associated with a decreased risk of Parkinson's disease; however, it is unknown whether this is due to people with healthier brain dopaminergic reward centers (the area of the brain affected by Parkinson's) being more likely to enjoy smoking and thus pick up the habit, nicotine directly acting as a neuroprotective agent, or other ...