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The surface of the nanoparticle, if not already hydrophobic, may have polymers attached to the surface to adjust the current polarity. Ligands can also be attached to the surface of a nanoparticle to target certain receptors located within the brain. Once the nanoparticle is through the blood brain barrier it releases the drug into the brain. [5]
The volume of body fluid, blood glucose, oxygen, and carbon dioxide levels are also tightly homeostatically maintained. The volume of extracellular fluid in a young adult male of 70 kg (154 lbs) is 20% of body weight – about fourteen liters. Eleven liters are interstitial fluid and the remaining three liters are plasma. [7]
The surface-area-to-volume ratio has physical dimension inverse length (L −1) and is therefore expressed in units of inverse metre (m −1) or its prefixed unit multiples and submultiples. As an example, a cube with sides of length 1 cm will have a surface area of 6 cm 2 and a volume of 1 cm 3. The surface to volume ratio for this cube is thus
The kidneys measure the oxygen content rather than the partial pressure of oxygen in the arterial blood. When the oxygen content of the blood is chronically low, oxygen-sensitive cells secrete erythropoietin (EPO) into the blood. [53] The effector tissue is the red bone marrow which produces red blood cells (RBCs, also called erythrocytes).
The process of breathing does not fill the alveoli with atmospheric air during each inhalation (about 350 ml per breath), but the inhaled air is carefully diluted and thoroughly mixed with a large volume of gas (about 2.5 liters in adult humans) known as the functional residual capacity which remains in the lungs after each exhalation, and ...
This glossary of biology terms is a list of definitions of fundamental terms and concepts used in biology, the study of life and of living organisms.It is intended as introductory material for novices; for more specific and technical definitions from sub-disciplines and related fields, see Glossary of cell biology, Glossary of genetics, Glossary of evolutionary biology, Glossary of ecology ...
C a = the oxygen concentration of arterial blood (oxygenated blood) C v = the oxygen concentration of venous blood (deoxygenated blood) The usual unit for a-vO 2 diff is millilitres of oxygen per 100 millilitres of blood (mL/100 mL), [1] however, particularly in medical uses, other units may be used, such as micro moles per millilitre (μmol/mL ...
The glycocalyx is located on the apical surface of vascular endothelial cells which line the lumen.When vessels are stained with cationic dyes such as Alcian blue stain, transmission electron microscopy shows a small, irregularly shaped layer extending approximately 50–100 nm into the lumen of a blood vessel.