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4018 n/a Ensembl ENSG00000198670 n/a UniProt P08519 n/a RefSeq (mRNA) NM_005577 n/a RefSeq (protein) n/a n/a Location (UCSC) Chr 6: 160.53 – 160.66 Mb n/a PubMed search n/a Wikidata View/Edit Human Lipoprotein(a) is a low-density lipoprotein variant containing a protein called apolipoprotein(a). Genetic and epidemiological studies have identified lipoprotein(a) as a risk factor for ...
“High lipoprotein(a) impacts one in five globally…And it's not just the individual, it's the families, because each child born to someone with it has a 50% chance of inheriting it.”
and LDL-C reduction is indicated if the count in mg/dL is over... High, meaning a 20% or greater risk of heart attack within 10 years, or an extreme risk factor 70 [54] 100 [54] moderately high, meaning a 10-20% risk of heart attack within 10 years and more than 2 heart attack risk factors 100 [54] 130 [54]
About 13% — roughly 3,600 participants — had either a heart attack or stroke, had surgery to fix a narrowed or blocked artery, or died from heart disease over the 30-year follow-up period.
Hyperlipidemia is abnormally high levels of any or all lipids (e.g. fats, triglycerides, cholesterol, phospholipids) or lipoproteins in the blood. [2] The term hyperlipidemia refers to the laboratory finding itself and is also used as an umbrella term covering any of various acquired or genetic disorders that result in that finding. [3]
A lipoprotein is a biochemical assembly whose primary function is to transport hydrophobic lipid (also known as fat) molecules in water, as in blood plasma or other extracellular fluids. They consist of a triglyceride and cholesterol center, surrounded by a phospholipid outer shell, with the hydrophilic portions oriented outward toward the ...
(One extreme exception, lipoprotein apheresis, is an efficient but time-consuming way of clearing lipoprotein through “sort of a dialysis for cholesterol,” reserved for only the highest-risk ...
• Remnant Lipoprotein cholesterol (RLP-C) levels are an independent predictor of the incidents of CHD in two primary prevention cohorts: Jackson Heart Study & Framingham Offspring Cohort Study.4 • Low HDL3-C, but not HDL2-C or HDL-C, independently increased the risk for long-term hard clinical events in secondary prevention patients: TRIUMPH.5