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Bradycardia; Hypertension (high blood pressure); Allergic reactions (e.g. dyspnoea (shortness of breath), bronchospasm, wheezing, angioneurotic oedema) Anaphylaxis; Changes in appetite
[36] [37] Other side effects may result from interactions with other medications. Tramadol has the same dose-dependent adverse effects as morphine including respiratory depression. [38] Main side effects of tramadol: Red color denotes more serious effects, requiring immediate contact with health provider. [3]
It is similar to tramadol in its dual mechanism of action; namely, its ability to activate the μ-opioid receptor and inhibit the reuptake of norepinephrine. [13] Unlike tramadol, it has only weak effects on the reuptake of serotonin and is a significantly more potent opioid with no known active metabolites. [13] [15]
Rare Side Effects of Sildenafil 100mg. Although rare, sildenafil can also cause more serious side effects, including some that may need immediate medical attention. Severe side effects include:
Today, pharmaceutical companies try to make new drugs as selective as possible to minimise binding to antitargets and hence reduce the occurrence of side effects and risk of adverse reactions. Examples of compounds often cited as "dirty drugs" include tramadol , chlorpromazine , olanzapine , dextromethorphan , ibogaine , and ethanol , all of ...
COX-2 selective inhibitors have fewer gastrointestinal side effects, but promote thrombosis, and some of these agents substantially increase the risk of heart attack. As a result, certain COX-2 selective inhibitors—such as rofecoxib —are no longer used due to the high risk of undiagnosed vascular disease . [ 11 ]
The maximum concentration of umifenovir in blood plasma when taking a dose of 50 mg is achieved after 1.2 hours, with 100 mg the maximum dose is obtained after 1.5 hours. [3] The bioavailability of the drug is about 40% and does not depend on food intake. [3] The half-life is about 17-21 hours.
His cholesterol levels exceeded 1,000 mg per deciliter, far higher than his baseline level, between 210 and 300 mg. Normal cholesterol ranges for adults are below 200 mg, five times lower than ...