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Moderately stable. Potency is retained at high temperature and also can be stored frozen at -20 °C. Meningococcal [37] PS Lyophilized None 2° - 8 °C Not freeze sensitive as most of the vaccines need to be stored frozen. Have good stability at room temperature. PS-PVC Liquid or Lyophilized AlOH3/None 2° - 8 °C
The USP Controlled Room Temperature is a series of United States Pharmacopeia guidelines for the storage of pharmaceuticals; [1] the relevant omnibus standard is USP 797. [2] [3] Although 100% compliance remains challenging for any given facility, [4] the larger protocol may be regarded as constituting a form of clean room [5] which is included in a suite of best practices.
The upper critical solution temperature (UCST) or upper consolute temperature is the critical temperature above which the components of a mixture are miscible in all proportions. [1] The word upper indicates that the UCST is an upper bound to a temperature range of partial miscibility, or miscibility for certain compositions only.
[1] With stability testing, pharmaceutical industry inspects the quality of drug substances and drug products as per the guidelines outlined by US Food and Drug Administration and International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use to make sure that they retained the quality over the period of time.
A digital thermometer reading an ambient temperature of 36.4°C (97°F) in an unventilated room during a heat wave; a high indoor temperature can cause heat exhaustion or heat stroke in a person. The World Health Organization in 1987 found that comfortable indoor temperatures of 18–24 °C (64–75 °F) were not associated with health risks ...
Crystal structure of β-glucosidase from Thermotoga neapolitana (PDB: 5IDI).Thermostable protein, active at 80°C and with unfolding temperature of 101°C. [1]In materials science and molecular biology, thermostability is the ability of a substance to resist irreversible change in its chemical or physical structure, often by resisting decomposition or polymerization, at a high relative ...
The working fluid is 3 He, which is circulated by vacuum pumps at room temperature. The 3 He enters the cryostat at a pressure of a few hundred millibar . In the classic dilution refrigerator (known as a wet dilution refrigerator ), the 3 He is precooled and purified by liquid nitrogen at 77 K and a 4 He bath at 4.2 K.
Temperature-responsive polymers or thermoresponsive polymers are polymers that exhibit drastic and discontinuous changes in their physical properties with temperature. [1] The term is commonly used when the property concerned is solubility in a given solvent , but it may also be used when other properties are affected.
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