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There are two types of active transport: primary active transport that uses adenosine triphosphate (ATP), and secondary active transport that uses an electrochemical gradient. This process is in contrast to passive transport , which allows molecules or ions to move down their concentration gradient, from an area of high concentration to an area ...
Secondary active transport is when one solute moves down the electrochemical gradient to produce enough energy to force the transport of another solute from low concentration to high concentration. [ citation needed ] An example of where this occurs is in the movement of glucose within the proximal convoluted tubule (PCT).
As the cotransport of glucose with sodium from the lumen does not directly require ATP hydrolysis but depends upon the action of the ATPase, this is described as secondary active transport. [10] There are two types of secondary active transporter found within the kidney tubule; close to the glomerulus, where glucose levels are high, SGLT2 has a ...
These proteins can be involved in transport in a number of ways: they act as pumps driven by ATP, that is, by metabolic energy, or as channels of facilitated diffusion. Transport of substances across the plasma membrane can be via passive transport (simple and facilitated diffusion) or active transport.
In cell biology, diffusion is a main form of transport for necessary materials such as amino acids within cells. [1] Diffusion of solvents, such as water, through a semipermeable membrane is classified as osmosis. Metabolism and respiration rely in part upon diffusion in addition to bulk
Crane in 1961 was the first to formulate the cotransport concept to explain active transport. Specifically, he proposed that the accumulation of glucose in the intestinal epithelium across the brush border membrane was [is] coupled to downhill Na+ transport cross the brush border. This hypothesis was rapidly tested, refined, and extended [to ...
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Comparison of transport proteins. A symporter is an integral membrane protein that is involved in the transport of two (or more) different molecules across the cell membrane in the same direction. The symporter works in the plasma membrane and molecules are transported across the cell membrane at the same time, and is, therefore, a type of ...