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  2. Smallpox - Wikipedia

    en.wikipedia.org/wiki/Smallpox

    Smallpox was an infectious disease caused by variola virus (often called smallpox virus), which belongs to the genus Orthopoxvirus. [7] [11] The last naturally occurring case was diagnosed in October 1977, and the World Health Organization (WHO) certified the global eradication of the disease in 1980, [10] making smallpox the only human disease to have been eradicated to date.

  3. Eradication of infectious diseases - Wikipedia

    en.wikipedia.org/wiki/Eradication_of_infectious...

    Smallpox is the first disease, and so far the only infectious disease of humans, to be eradicated by deliberate intervention. [6] It became the first disease for which there was an effective vaccine in 1798 when Edward Jenner showed the protective effect of inoculation (vaccination) of humans with material from cowpox lesions. [10]

  4. Diseases and epidemics of the 19th century - Wikipedia

    en.wikipedia.org/wiki/Diseases_and_epidemics_of...

    The words come from various (spotted) or varus (pimple). In England, this disease was first known as the "pox" or the "red plague". Smallpox settles itself in small blood vessels of the skin and in the mouth and throat. The symptoms of smallpox are rash on the skin and blisters filled with raised liquid. [citation needed]

  5. Smallpox vaccine - Wikipedia

    en.wikipedia.org/wiki/Smallpox_vaccine

    The smallpox vaccine is used to prevent smallpox infection caused by the variola virus. [10] It is the first vaccine to have been developed against a contagious disease. In 1796, British physician Edward Jenner demonstrated that an infection with the relatively mild cowpox virus conferred immunity against the deadly smallpox virus.

  6. Ali Maow Maalin - Wikipedia

    en.wikipedia.org/wiki/Ali_Maow_Maalin

    No treatment is available, and the only protection is vaccination. The virus is usually transmitted by prolonged face-to-face contact with a person showing symptoms. The incubation period averages 12–14 days. [18] One of the most feared diseases of human history, smallpox was still causing an estimated 2 million deaths every year as late as 1967.

  7. Variolation - Wikipedia

    en.wikipedia.org/wiki/Variolation

    In contrast, infection of the skin usually led to a milder, localized infection, but, crucially, still induced immunity to the virus. The patient would develop pustules like those caused by naturally acquired smallpox. Eventually, after about two to four weeks, these symptoms would subside, indicating successful recovery and immunity.

  8. Fact check: Can your childhood smallpox vaccine protect ... - AOL

    www.aol.com/news/fact-check-childhood-smallpox...

    According to the CDC, monkeypox is closely related to the virus that causes smallpox. Both the CDC and the WHO have published data showing that the smallpox vaccine is 85% effective in preventing ...

  9. History of smallpox - Wikipedia

    en.wikipedia.org/wiki/History_of_smallpox

    The history of smallpox extends into pre-history. [1] Genetic evidence suggests that the smallpox virus emerged 3,000 to 4,000 years ago. [2] Prior to that, similar ancestral viruses circulated, but possibly only in other mammals, and possibly with different symptoms.