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Iodine deficiency is a lack of the trace element iodine, an essential nutrient in the diet.It may result in metabolic problems such as goiter, sometimes as an endemic goiter as well as congenital iodine deficiency syndrome due to untreated congenital hypothyroidism, which results in developmental delays and other health problems.
Where natural levels of iodine in the soil are low and vegetables do not take up the iodine, iodine added to salt provides the small but essential amount of iodine needed by humans. An opened package of table salt with iodide may rapidly lose its iodine content in high temperature and high relative humidity conditions through the process of ...
Iodine deficiency is the most common cause of primary hypothyroidism and endemic goiter worldwide. [8] [9] In areas of the world with sufficient dietary iodine, hypothyroidism is most commonly caused by the autoimmune disease Hashimoto's thyroiditis (chronic autoimmune thyroiditis). [8] [9] Hashimoto's may be associated with a goiter.
T 3 and T 4 are partially composed of iodine, derived from food. [2] A deficiency of iodine leads to decreased production of T 3 and T 4, enlarges the thyroid tissue and will cause the disease known as simple goitre. [3] The major form of thyroid hormone in the blood is thyroxine (T 4), whose half-life of around one week [4] is longer than that ...
Mutations in the gene encoding iodotyrosine deiodinase can affect enzyme function and be detrimental to human health. Iodide is an essential micronutrient for health in mammals. [24] Low levels of iodide either through the diet or through iodide metabolism are associated with hypothyroidism, mental retardation, goiter, and developmental defects.
Iodine deficiency is the leading cause of preventable intellectual disability, a result that occurs primarily when babies or small children are rendered hypothyroidic by no iodine. The addition of iodine to salt has largely destroyed this problem in wealthier areas, but iodine deficiency remains a serious public health problem in poorer areas ...
Pregnant women deficient of iodine can give birth to infants with thyroid hormone deficiency. [73] [22] The use of iodised salt to add iodine to the diet [22] has eliminated endemic cretinism in most developed countries, [76] and over 120 countries have made the iodination of salt mandatory. [77] [78] Because the thyroid concentrates iodine, it ...
In areas where iodine-deficiency is not found, the most common type of hypothyroidism is an autoimmune subtype called Hashimoto's thyroiditis, with a prevalence of 1-2%. [40] As for hyperthyroidism, Graves' disease , another autoimmune condition, is the most common type with a prevalence of 0.5% in males and 3% in females. [ 41 ]