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Granulomatosis with polyangiitis; Other names: Wegener's granulomatosis (WG) (formerly) Micrograph showing features characteristic of granulomatosis with polyangiitis – a vasculitis and granulomas with multi-nucleated giant cells. H&E stain. Specialty: Immunology, rheumatology Causes: Autoimmune disease
Friedrich Wegener (7 April 1907, Varel – 9 July 1990, Lübeck, [veːɡɐnəɐ̯]) was a German pathologist who is notable for being a high-ranking Nazi physician and for his description of a rare disease originally referred to Wegener disease and now referred to as granulomatosis with polyangiitis. Although this disease was known before ...
Chronic granulomatous disease (CGD), also known as Bridges–Good syndrome, chronic granulomatous disorder, and Quie syndrome, [1] is a diverse group of hereditary diseases in which certain cells of the immune system have difficulty forming the reactive oxygen compounds (most importantly the superoxide radical due to defective phagocyte NADPH oxidase) used to kill certain ingested pathogens. [2]
Granulomatosis with polyangiitis (GPA) Small to medium vessels in respiratory tract, kidneys c-ANCA/PR3-ANCA Confirmed [36] IgA vasculitis (IgAV) Small vessels in skin, joints, kidneys, gastrointestinal tract IgA immune complexes Probable [37] Leukocytoclastic vasculitis: Small vessels in skin Various immune complexes Probable [38] Lupus vasculitis
Friedrich Wegener: Granulomatosis with polyangiitis: Wegener was a member of several Nazi organizations such as the National Socialist German Workers' Party, the Storm Troopers, and the Reich Air Protection League before World War II. In 1941 and 1942, Wegener made oaths of allegiance to Adolf Hitler saying "I pledge: I will be loyal and ...
Wegener's granulomatosis (now known as granulomatosis with polyangiitis) Wegmann–Jones–Smith syndrome; Weil syndrome; Weinstein–Kliman–Scully syndrome; Weismann–Netter–Stuhl syndrome; Weissenbacher–Zweymuller syndrome; Welander distal myopathy, Swedish type; Weleber–Hecht–Bigley syndrome; Wellesley–Carmen–French syndrome
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Eosinophilic granulomatosis with polyangiitis consists of three stages, but not all patients develop all three stages or progress from one stage to the next in the same order; [7] whereas some patients may develop severe or life-threatening complications such as gastrointestinal involvement and heart disease, some patients are only mildly affected, e.g. with skin lesions and nasal polyps. [8]